Biaryl synthesis via palladium-catalyzed aryne multicomponent coupling

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Abstract

Aryl iodides have been introduced as electrophiles in the three-component Heck coupling of arynes. Following optimization studies to favor three- versus two-component coupling, the reaction proceeds in good yield to afford a variety of functionalized biaryls. © 2007 American Chemical Society.

Bibliographical metadata

Original languageEnglish
Pages (from-to)5589-5592
Number of pages3
JournalOrganic Letters
Volume9
Issue number26
DOIs
StatePublished - 20 Dec 2007