Au-catalyzed cross-coupling of arenes via double C–H activation

Research output: Contribution to journalArticle

  • Authors:
  • Xacobe Cambeiro
  • Nanna Ahlsten
  • Igor Larrosa

Abstract

The first methodology for Au(I/III)-catalyzed oxidative cross-coupling of arenes via double C–H activation has been developed. The reaction is fully selective for the cross-coupling between electron-rich hetero-/carbocyclic arenes and electron-poor arenes bearing relatively acidic C–H bonds. The inherently high cross-selectivity of the system obviates the need for directing groups or a large excess of one of the coupling partners.

Bibliographical metadata

Original languageEnglish
JournalAmerican Chemical Society. Journal
DOIs
StatePublished - 8 Dec 2015