An ex-vivo evaluation of tomographic 3D ultrasound, B-Mode ultrasound, CT and MR imaging to measure artery diameter, length and wall-volume.

Research output: Contribution to journalArticlepeer-review

  • External authors:
  • Joao Carreira
  • Ruth Thompson
  • Ana Morais
  • Wolfgang Wein
  • Jonathan Ghosh

Abstract

Precise measurement of luminal diameter in arteries is important when planning interventional vascular procedures in patients. Measuring wall volume may be important in detecting early artery disease and in the assessment of treatments to prevent atherosclerosis. An ex-vivo phantom using porcine arteries was used to evaluate the accuracy with which i) B-mode ultrasound, ii) tomographic 3D ultrasound (tUS), iii) Computed-Tomography and iv) Magnetic-Resonance imaging measured length, diameters and volume. The mean error in inner-to-inner diameter measurements by B-mode, tUS, CT and MRI were 0.08±0.26mm, -0.73±0.96mm, 0.09±0.55mm and 0.60±1.01mm respectively. The mean error in outer-to-outer diameter measurements by B-mode, tUS, CT and MRI were -1.33±0.61mm, -1.03±0.35mm, 0.02±1.00mm and -0.47±1.32mm respectively. The mean error in volume measurements by B-mode, tUS, CT and MRI were -0.54±0.62cm3, -0.06±0.09 cm3, 0.01±0.18 cm3 and -0.20±0.32 cm3 respectively. Errors in length and diameters remain within clinically acceptable thresholds where MR was the least accurate. tUS was the most accurate method of volume measurement

Bibliographical metadata

Original languageEnglish
JournalUltrasound in Medicine and Biology
Early online date30 Jul 2019
DOIs
Publication statusPublished - 2019