An analytic dosimetry study for the use of radionuclide liposome conjugates in internal radiotherapy

Research output: Contribution to journalArticle

Abstract

A dosimetric analysis has been performed to evaluate the potential of liposome systems as carriers of radionuclides in internal radiotherapy. Methods: Pharmacokinetic data for a variety of liposome constructs (multilamellar vesicles [MLV]; small unilamellar vesicles [SUV]; and sterically stabilized liposomes, monosialoganglioside [GM1]-coated) were used to obtain tumor and normal-organ absorbed dose estimates for 67Cu, 188Re, 90Y, and 131I.

Bibliographical metadata

Original languageEnglish
Pages (from-to)499-504
JournalThe journal of Nuclear Medicine
Volume42
Issue number3
Publication statusPublished - 2001