A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A

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Abstract

A template-based mnemonic has been developed for the enzyme monoamine oxidase from Aspergillus niger and has been used to successfully identify the alkaloid (±)-crispine A as a target for chemo-enzymatic deracemisation yielding the biologically active (R)-enantiomer in 97% e.e. © The Royal Society of Chemistry.

Bibliographical metadata

Original languageEnglish
Pages (from-to)3640-3642
Number of pages2
JournalChemical Communications
Issue number35
DOIs
Publication statusPublished - 2007