A Role for Notch Signalling in Breast Cancer and Endocrine Resistance.Citation formats

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A Role for Notch Signalling in Breast Cancer and Endocrine Resistance. / Acar, Ahmet; Simões, Bruno M; Clarke, Robert B; Brennan, Keith.

In: Stem cells international, Vol. 2016, 2016.

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@article{21974ef47f174fb0bf2fac1a82c9a17b,
title = "A Role for Notch Signalling in Breast Cancer and Endocrine Resistance.",
abstract = "Over the past decade, there has been growing interest in the Notch signalling pathway within the breast cancer field. This interest stemmed initially from the observation that Notch signalling is aberrantly activated in breast cancer and its effects on various cellular processes including proliferation, apoptosis, and cancer stem cell activity. However more recently, elevated Notch signalling has been correlated with therapy resistance in oestrogen receptor-positive breast cancer. As a result, inhibiting Notch signalling with therapeutic agents is being explored as a promising treatment option for breast cancer patients.",
author = "Ahmet Acar and Sim{\~o}es, {Bruno M} and Clarke, {Robert B} and Keith Brennan",
year = "2016",
doi = "10.1155/2016/2498764",
language = "English",
volume = "2016",
journal = "Stem cells international",
issn = "1687-966X",

}

RIS

TY - JOUR

T1 - A Role for Notch Signalling in Breast Cancer and Endocrine Resistance.

AU - Acar, Ahmet

AU - Simões, Bruno M

AU - Clarke, Robert B

AU - Brennan, Keith

PY - 2016

Y1 - 2016

N2 - Over the past decade, there has been growing interest in the Notch signalling pathway within the breast cancer field. This interest stemmed initially from the observation that Notch signalling is aberrantly activated in breast cancer and its effects on various cellular processes including proliferation, apoptosis, and cancer stem cell activity. However more recently, elevated Notch signalling has been correlated with therapy resistance in oestrogen receptor-positive breast cancer. As a result, inhibiting Notch signalling with therapeutic agents is being explored as a promising treatment option for breast cancer patients.

AB - Over the past decade, there has been growing interest in the Notch signalling pathway within the breast cancer field. This interest stemmed initially from the observation that Notch signalling is aberrantly activated in breast cancer and its effects on various cellular processes including proliferation, apoptosis, and cancer stem cell activity. However more recently, elevated Notch signalling has been correlated with therapy resistance in oestrogen receptor-positive breast cancer. As a result, inhibiting Notch signalling with therapeutic agents is being explored as a promising treatment option for breast cancer patients.

U2 - 10.1155/2016/2498764

DO - 10.1155/2016/2498764

M3 - Article

VL - 2016

JO - Stem cells international

JF - Stem cells international

SN - 1687-966X

ER -