In this paper we present how by analysing the diversity of a system we can estimate the impact of an enterprise interoperability tool to a business ecosystem. We report experimental results on using a multi-agent system to simulate a business ecosystem in which we introduce the local effect of Commius, a low-cost interoperability tool for SMEs, into business collaborative interactions. The importance of the results derives from the egocentric attention commonly paid to the collaboration boost brought to the company using this sort of tools without considering the side effects it could bring to the network, where more than one company can also use it. When we apply our results to a cluster of companies, experiments indicate that an interoperability indeed adds dynamism to the network, yet it does not improve the network's capability of resilience. © 2011 IEEE.