A bi-directional assessment of the human brain-anorectal axisCitation formats

  • External authors:
  • J. M. Remes-Troche
  • K. Tantiphlachiva
  • A. Attaluri
  • J. Valestin
  • T. Yamada
  • S. S C Rao

Standard

A bi-directional assessment of the human brain-anorectal axis. / Remes-Troche, J. M.; Tantiphlachiva, K.; Attaluri, A.; Valestin, J.; Yamada, T.; Hamdy, S.; Rao, S. S C.

In: Neurogastroenterology and Motility, Vol. 23, No. 3, 03.2011, p. 240-e118.

Research output: Contribution to journalArticle

Harvard

Remes-Troche, JM, Tantiphlachiva, K, Attaluri, A, Valestin, J, Yamada, T, Hamdy, S & Rao, SSC 2011, 'A bi-directional assessment of the human brain-anorectal axis', Neurogastroenterology and Motility, vol. 23, no. 3, pp. 240-e118. https://doi.org/10.1111/j.1365-2982.2010.01619.x

APA

Remes-Troche, J. M., Tantiphlachiva, K., Attaluri, A., Valestin, J., Yamada, T., Hamdy, S., & Rao, S. S. C. (2011). A bi-directional assessment of the human brain-anorectal axis. Neurogastroenterology and Motility, 23(3), 240-e118. https://doi.org/10.1111/j.1365-2982.2010.01619.x

Vancouver

Remes-Troche JM, Tantiphlachiva K, Attaluri A, Valestin J, Yamada T, Hamdy S et al. A bi-directional assessment of the human brain-anorectal axis. Neurogastroenterology and Motility. 2011 Mar;23(3):240-e118. https://doi.org/10.1111/j.1365-2982.2010.01619.x

Author

Remes-Troche, J. M. ; Tantiphlachiva, K. ; Attaluri, A. ; Valestin, J. ; Yamada, T. ; Hamdy, S. ; Rao, S. S C. / A bi-directional assessment of the human brain-anorectal axis. In: Neurogastroenterology and Motility. 2011 ; Vol. 23, No. 3. pp. 240-e118.

Bibtex

@article{5e106682ae2e4b8389d5f6471f522903,
title = "A bi-directional assessment of the human brain-anorectal axis",
abstract = "Background Brain-gut dysfunction has been implicated in gastrointestinal disorders but a comprehensive test of brain-gut axis is lacking. We developed and tested a novel method for assessing both afferent anorectal-brain function using cortical evoked potentials (CEP), and efferent brain-anorectal function using motor evoked potentials (MEP). Methods Cortical evoked potentials was assessed following electrical stimulations of anus and rectum with bipolar electrodes in 26 healthy subjects. Anorectal MEPs were recorded following transcranial magnetic stimulation (TMS) over paramedian motor cortices bilaterally. Anal and rectal latencies/amplitudes for CEP and MEP responses and thresholds for first sensation and pain (mA) were analyzed and compared. Reproducibility and interobserver agreement of responses were examined. Key Results Reproducible polyphasic rectal and anal CEPs were recorded in all subjects, without gender differences, and with negative correlation between BMI and CEP amplitude (r -0.66, P=0.001). Transcranial magnetic stimulation evoked triphasic rectal and anal MEPs, without gender differences. Reproducibility for CEP and MEP was excellent (CV",
keywords = "Anorectal sensation, Brain-gut, Cortical evoked potentials, Transcranial magnetic stimulation",
author = "Remes-Troche, {J. M.} and K. Tantiphlachiva and A. Attaluri and J. Valestin and T. Yamada and S. Hamdy and Rao, {S. S C}",
year = "2011",
month = "3",
doi = "10.1111/j.1365-2982.2010.01619.x",
language = "English",
volume = "23",
pages = "240--e118",
journal = "Neurogastroenterology and Motility",
issn = "1350-1925",
publisher = "John Wiley & Sons Ltd",
number = "3",

}

RIS

TY - JOUR

T1 - A bi-directional assessment of the human brain-anorectal axis

AU - Remes-Troche, J. M.

AU - Tantiphlachiva, K.

AU - Attaluri, A.

AU - Valestin, J.

AU - Yamada, T.

AU - Hamdy, S.

AU - Rao, S. S C

PY - 2011/3

Y1 - 2011/3

N2 - Background Brain-gut dysfunction has been implicated in gastrointestinal disorders but a comprehensive test of brain-gut axis is lacking. We developed and tested a novel method for assessing both afferent anorectal-brain function using cortical evoked potentials (CEP), and efferent brain-anorectal function using motor evoked potentials (MEP). Methods Cortical evoked potentials was assessed following electrical stimulations of anus and rectum with bipolar electrodes in 26 healthy subjects. Anorectal MEPs were recorded following transcranial magnetic stimulation (TMS) over paramedian motor cortices bilaterally. Anal and rectal latencies/amplitudes for CEP and MEP responses and thresholds for first sensation and pain (mA) were analyzed and compared. Reproducibility and interobserver agreement of responses were examined. Key Results Reproducible polyphasic rectal and anal CEPs were recorded in all subjects, without gender differences, and with negative correlation between BMI and CEP amplitude (r -0.66, P=0.001). Transcranial magnetic stimulation evoked triphasic rectal and anal MEPs, without gender differences. Reproducibility for CEP and MEP was excellent (CV

AB - Background Brain-gut dysfunction has been implicated in gastrointestinal disorders but a comprehensive test of brain-gut axis is lacking. We developed and tested a novel method for assessing both afferent anorectal-brain function using cortical evoked potentials (CEP), and efferent brain-anorectal function using motor evoked potentials (MEP). Methods Cortical evoked potentials was assessed following electrical stimulations of anus and rectum with bipolar electrodes in 26 healthy subjects. Anorectal MEPs were recorded following transcranial magnetic stimulation (TMS) over paramedian motor cortices bilaterally. Anal and rectal latencies/amplitudes for CEP and MEP responses and thresholds for first sensation and pain (mA) were analyzed and compared. Reproducibility and interobserver agreement of responses were examined. Key Results Reproducible polyphasic rectal and anal CEPs were recorded in all subjects, without gender differences, and with negative correlation between BMI and CEP amplitude (r -0.66, P=0.001). Transcranial magnetic stimulation evoked triphasic rectal and anal MEPs, without gender differences. Reproducibility for CEP and MEP was excellent (CV

KW - Anorectal sensation

KW - Brain-gut

KW - Cortical evoked potentials

KW - Transcranial magnetic stimulation

U2 - 10.1111/j.1365-2982.2010.01619.x

DO - 10.1111/j.1365-2982.2010.01619.x

M3 - Article

VL - 23

SP - 240-e118

JO - Neurogastroenterology and Motility

JF - Neurogastroenterology and Motility

SN - 1350-1925

IS - 3

ER -