A [13]rotaxane assembled via a palladium molecular capsule

Research output: Contribution to journalArticlepeer-review

  • External authors:
  • Jesus Ferrando Soria
  • Antonio Fernandez Mato
  • Deepak Asthana
  • Selina Nawaz
  • Inigo Vitorica-Yrezabal
  • George Whitehead
  • Christopher Muryn
  • Grigore Timco
  • Neil Burton

Abstract

Molecules that are the size of small proteins are difficult to make. The most frequently examined route is via self-assembly, and one particular approach involves molecular nanocapsules, where ligands are designed that will enforce the formation of specific polyhedra of metals within the core of the structure. Here we show that this approach can be combined with mechanically interlocking molecules to produce nanocapsules that are decorated on their exterior. This could be a general route to very large molecules, and is exemplified here by the synthesis and structural characterization of a [13]rotaxane, containing 150 metal centres. Small angle X-ray scattering combined with atomistic molecular dynamics simulations demonstrate the compound is intact in solution.

Bibliographical metadata

Original languageEnglish
Article number3720
JournalNature Communications
Volume10
DOIs
Publication statusPublished - 16 Aug 2019

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