Biography

Postdoctoral Appointments
2011 Lecturer in Evolutionary Biology and Postgraduate Tutor, Manchester
2008 NERC Research Fellow, Manchester
2005 Postdoctoral Research Associate, Manchester
2004 Postdoctoral Research Assistant, Cambridge

Education
2004 PhD, Trinity College, University of Cambridge
1999 MSc (Diplom-Biologe), University of Würzburg
1996-1997 Undergraduate studies in biology, University of Edinburgh
1993-1996 Undergraduate studies in economics, psychology, law and biology, Universities of Kassel, Munich and Stuttgart


Awards & Distinctions
2009-2014 DFG Emmy Noether Group Leader, LMU Munich (declined)
2009         World Health Summit, Berlin, invitation
2008-2011 NERC Research Fellowship
2005-2007 DFG Emmy Noether Research Fellowship
2002-2003 Senior Rouse Ball Scholarship, Trinity College

External and Internal Committees

2012-present Natural Environment Research Council: Peer Review College
2011-present Research Degree Committee
2008-present General Assembly
2012-2015 Board of Governors
2012-2015 Senate
2014-2015 University Staffing Committee

Dissemination
Plenaries: 6 international plenaries
Seminars: 33 invited University seminars, 47 conference contributions
Media: research featured in numerous international media, e.g. Der Standard, Der Tagespiegel, Nature, Noorderlicht, Science, Westdeutsche Rundfunk, BBC News

Editorial Boards
2014-present  BMC Genetics, Associate Editor
2010-2014      Frontiers in Genetics of Complex Traits, Review Editor

Non-Academic Roles
2013-present  The Portico Trust Charity: Vice Chairman
2012-present  The Portico Library, Manchester: Main Committee

 

Publications Summary (Peer-reviewed)
First or last author:  43
Total number:          48
Book: Hager R, Jones CB. 2009. Reproductive Skew. Cambridge UP.

 

Key Publications
 

Ashbrook DG, Gini B, Hager R. 2016. Genetic variation in offspring indirectly influences the quality of maternal behaviour in mice. eLife 10.7554/eLife.11814

Hager R, Lu L, Rosen GD, Williams RW. 2012. Genetic architecture supports mosaic brain evolution and independent brain-body regulation. Nature Communications, 3, 1079.

Nonacs P, Hager R. 2011. The past, present and future of reproductive skew theory and experiments. Biological Reviews, 86, 271-298.

Cheverud JM, Hager R, Roseman C, Fawcett G, Wang B, Wolf JB. 2008. Genomic imprinting effects on adult body composition in mice. PNAS, 105, 4253-4258.

Wolf JB, Cheverud JM, Roseman C, Hager R. 2008. Genome-wide analysis reveals a complex pattern of genomic imprinting in mice. PLoS Genetics, 4, e1000091.

Wolf JB, Hager R. 2006. A maternal-offspring coadaptation theory for the evolution of genomic imprinting. PLoS Biology, 4(12)

Hager R, Johnstone RA. 2003. The genetic basis of family conflict resolution in mice. Nature, 421, 533-535.

Roulin A, Hager R. 2003. Indiscriminate nursing in communal breeders: A role for genomic imprinting. Ecology Letters

Overview

Reinmar Hager is an evolutionary biologist with an interest in the role of genetic and epigenetic effects in family interactions, individual development and coadaptation between parental and offspring traits. A particular focus of recent research has been the phenotypic analysis of genomic imprinting effects on variation in complex traits using a quantitative trait locus approach. Reinmar is currently investigating how phenotypic variation caused by genomic imprinting can depend on social environment and sex. Moreover, he is conducting research on the genetics of parent-offspring conflict resolution in recombinant inbred mice, using a systems-genetics approach to understand how genes expressed in other animals affect the phenotype and behaviour of a focal animal, and testing whether brain evolution in mammals follows a mosaic or concerted pattern. Other research interests are in behavioural ecology, in particular the evolution of sociality. He has recently edited a book on reproductive skew, published by Cambridge University Press.

Research interests

Research

The genetic and epigenetic basis of quantitative traits involved in family conflicts and coadaptation
The genetic and epigenetic basis of quantitative traits involved in family conflicts and coadaptation

The genetic and epigenetic basis of quantitative traits involved in family conflicts and coadaptation

Here, we investigate the genetic and epigenetic basis of quantitative traits involved in family conflicts and coadaptation. Conceptually, the main focus of this research is on traits involved in interactions between family members and their underlying genetic and epigenetic basis. Interactions between family members are characterized by conflict over resource allocation (i.e. parent-offspring, sexual and sibling conflict) and synergistic or negative coadaptation between fitness-related traits. Previous empirical research has uncovered evidence for antagonistic coevolution between distinct life history traits in male and female mice as well as coadaptation between maternal provisioning and offspring maternal genotype. Using recombinant inbred mouse panels (BXD) we are currently investigating the genetic architecture of a number of different complex traits such as growth, maternal provisioning and behavioural phenotypes. Furthermore, we conduct research into the genetics of parent-offspring conflict and coadaptation between offspring and maternal traits to test assumptions and predictions of conflict resolution and coadaptation models.

Quantitative trait loci analysis of epigenetic effects on complex traits

The focus of this project with Jason Wolf and James Cheverud is on the role of genomic imprinting and maternal effects in complex trait variation. One aim is to develop and apply statistical tools to identify quantitative trait loci (QTL) across the genome for traits of interest and to assess the relative importance of genetic versus epigenetic effects for phenotypic variation in an intercross of Large and Small inbred mice.

Reproductive skew in animal societies
Reproductive skew in animal societies

Reproductive skew in animal societies

Reproductive skew theory investigates how reproduction is partitioned between group members and under what conditions stable groups can be predicted. The key objective lies in understanding how reproductive skew theory can be used as a framework to interpret the evolution of animal sociality. To this end I have recently edited a book with Clara B. Jones on this topic for Cambridge University Press. Currently, we are exploring how a quantitative genetics approach using agent based modelling can shed light on ultimate and proximate causes of skew.

The genetic basis of sociality

This project seeks to establish novel phenotyping protocols that allow the quantification of social behaviour for genetic analyses. A number of human disease phenotypes such as Williams Syndrome a

Teaching

BIOL10642 Africa Field Course in Animal Behaviour
BIOL30471 Advances in Behavioural Ecology

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