John McLaughlin is Professor of Gastroenterology and Nutrition and Head of the Division of Diabetes, Endocrinology and Gastroenterology in the Faculty of Biology, Medicine and Health at the University of Manchester.

His BSc Physiology (1st Class Hons) MB ChB (Hons) and PhD degrees were all awarded by Manchester. His research interests are gastrointestinal physiology in health and disease particularly the interactions between nutrients and the gut epithelium, gut inflammation, gut hormones, and gut-to-brain signalling. 

He trained in Gastroenterology and General Medicine in the North West Region also, with a period as an MRC Travelling Fellow at Harvard University. Spending 50% of his time as a Consultant Gastroenterologist he manages the clinical GI physiology service at Salford Royal University (Hope) Hospital, and leads the Comprehensive Local Research Network for Gastroenterology in Greater Manchester. He is Chair of the British Society of Gastroenterology Food and Function Clinical Research Group. Close clinical and academic links are also in place with other clinical areas in Salford.

The last 10 years have been highly invested in developing new clinical researchers, by close engagement with intercalating medical students undertaking a Masters in Research and by delivering training and mentorship to academic clinical fellows and lecturers in integrated training.

John was awarded the British Society of Gastroenterology's Francis Avery Jones Research Award in 2007, and the European Rising Star in Gastroenterology Award in 2008.

Memberships of committees and professional bodies

Section Committee, Neurogastroenterology and Motility, British Society of Gastroenterology.

Council member and programmes committee, British Society of Gastroenterology

Research Awards Committee, CORE (GI charity)

Editorial Board: 'Therapeutic Advances in Gastroenterology' and 'Frontiers in Gastrointestinal Pharmacology'

Specialist Training Committee for Gastroenterology, North West Deanery

Physiological Society

Bayliss and Starling Society

Royal College of Physicians


  • I am a clinical academic and my roles are split between 3 domains:
  • Teaching and Training: 
    • Programme Lead for North West Academic Clinical Lectureship Programme
  • Research: 
    • Multiple active projects with 7 current MD and PhD students
      • Lead for Comprehensive Local Research Network for Gastroenterology in Greater Manchester
      • British Society of Gastroenterology Food and Function Research Committee (Chair)
      • BBSRC Pool of Experts
      • Salford Hospital Clinical Trial Facility Steering Committee
  • Honorary Consultant Gastroenterologist, Salford Royal Hospitals: 50%
    • Lead Regional GI Physiology service


BSc (1st Class Hons) University of Manchester 1987

MB ChB (Hons) University of Manchester 1990

PhD University of Manchester 1998

MRCP(UK) 1993

CCST Gastoenterology and General Medicine 2002

FRCP (London) 2007

Research interests

Current research interests are all linked around central topics of the gastrointestinal response to food, gastrointestinal inflammation, appetite regulation, and the gut-brain axis.

Drawing on the strong Gastroenterology research history in Manchester, these activities have found broader relevance in an era of rapidly increasing obesity.

There is also a growing realisation that both diet and the microenvironment of the gut are pertinent to many other key areas of biomedical research, and particularly close links with the Faculty of Life Sciences and the food industry have consequently been forged. This is embodied in the cross-faculty 'Diet, Digestion and Health' group which I lead together with Dr Craig Smith in Life Sciences.

I also sit on the newly formed Salford Royal Hospitals Clinical Trial Facility Steering Committee.

  • Gastrointestinal physiology: clinical and basic
  • Nutrient sensing mechanisms in the gut
  • Inflammatory Bowel Disease: models and genes, clinical  practice and e-health
  • Appetite regulation in health and disease
  • The ageing gut
  • Enteroendocrine cells in health and disease
  • Diabetic gastroenteropathy
  • The epithelial barrier

 Research funded by MRC, BBSRC, CORE and Diabetes UK.


Teaching and training have been major components of my work, largely undertaken within Manchester Medical School:

Programme Lead for Academic Clinical Lecturers (North West Integrated Clinical Academic Training)

Intercalation Steering team (integrated clinical academic training rep), Manchester Medical School.

Programme Director MRes Medical Sciences (Intercalated Medical Students) 2007-2010

I have also developed the pilot MB PhD programme linked to the MRes

Current supervisor for 7 PhD/MD students

OSCE Examinder Salford Site

Academic Foundation Programme Board

Academic Foundation Tutor, Salford.

Clinical teaching and lectures

APEP tutor

Academic Advisor

Medical School Admissions Panels


ID: 422449