Jacky graduated in Medicine from Manchester University in 1992 and continued her training around the North West region in General and Respiratory Medicine. She only undertook research in her final year of specialist registrar training, taking time out to study for a PhD in the 'Measurement of Cough', awarded in 2004. This involved close collaboration with computer scientists and fuelled an interest in acoustics and signal processing. After completing specialist training she returned to research and was funded by a Stepping Stones Award from Manchester University and an MRC Clinician Scientists Fellowship Award until 2012.
In collaboration with Mr Kevin McGuinness (Clinical engineer) she has developed a novel method for automated cough detection. She is an inventor on a patent owned by the University Hospital of South Manchester, covering novel concepts for automated detection of cough from sound signals. This patent is the subject of a license agreement with a medical device company (Vitalograph) with whom she collaborates.
Whilst she continues to work on developing other endpoints in cough monitoring, her main research interests are in the translation of mechanisms of underlying cough reflex hypersensitivity and the testing of novel anti-tussive therapies.
Information about the cough clinic and clinical research can be found at www.combatmycough.com
Clinical research skills: bronchial challenge testing, cough reflex sensitivity testing, pulmonary function testing, exhaled nitric oxide measurement, sputum induction, endo-bronchial biopsy, brushing and lavage, optico-electronic plethysmography, intra-oesophageal and gastric balloon pressure measurements
Clinical trials experience: design, applying for ethical approval, patient recruitment, data collection and analysis, including clinical trials of investigational medicinal products for the treatment of cough.
Statistics and data analysis skills: I have an interest in advanced statistical techniques such as factor analysis, cluster analysis and recently structural equation modelling.
Signal Processing Skills: I have a basic understanding of acoustic signal processing and speech recognition techniques from a close collaboration with computer scientists and engineers
Jacky Smith is a Professor of Respiratory Medicine at the University of Manchester and an Honorary Consultant at the University Hospital of South Manchester NHS Foundation Trust. She runs a multi-disciplinary research team whose focus is on understanding mechanisms underlying pathological cough and a regional clinical service seeing patients with refractory chronic cough. She is also the Director of the NIHR South Manchester Respiratory and Allergy Clinical Research Facility and Specialty Lead for Respiratory in the Greater Manchester Clinical Research Network.
MB ChB Manchester 1992
MRCP London 1996
PhD Manchester 2004
Research interests include: