I completed my undergraduate medical training at the University of Birmingham Medical School. My pre-registration and general medical training were undertaken in the teaching hospitals of Birmingham. I trained in rheumatology at the Hammersmith Hospital, London; Guys Hospital, London and the teaching hospitals of Birmingham. My name was placed on the specialist register for rheumatology in 1986. I trained in Epidemiology at the University of Birmingham and at Erasmus University, Rotterdam, the Netherlands. I joined the Arthritis Research UK Epidemiology Unit in 1989. I was promoted to the Chair of Rheumatology and Musculoskeletal Epidemiology in 2001.
My main research interest is in the epidemiology of inflammatory musculoskeletal conditions – in particular, risk factors for the development and outcome of rheumatoid arthritis. I am a Principal Investigator for the Norfolk Arthritis Register and the BSR Biologics Register. I have a major interest in drug safety and pharmacoepidemiology. I was the Director of the NIHR Manchester Musculoskeletal BRU until April 2014, and remain the Lead for the Prevention of Co-Morbidity Research theme. I was the Director of the Arthritis Research UK Centre for Epidemiology until August 2014 and remain involved in the Norfolk Arthritis Register and BSR Biologics Register-RA programmes.