David Eisner (B.A. Cambridge, Natural Sciences, 1976; D.Phil Oxford, Physiology, 1979).

He spent the period 1980- 1990 in the Department of Physiology at University College London. From 1990-1999 he was Professor of Veterinary Biology at Liverpool University before moving to Manchester as Professor of Cardiac Physiology in October 1999.

He is currently Presidnet of The Physiological Society.  He has received the Pfizer Prize for Biology (1985), the Wellcome Prize in Physiology (1988) and given the QR Murphy lecture at the University of Wisconsin (1992), the Reimer Lecture of the International Society for Heart Research (2008), the Dorothy Wedgwood Lecture for Young People (2008), the  Peter Baker Memorial Lecture (2010), the Carmeliet-Coraboeuf-Weidmann Lecture of the European Working Group on Cardiac Cellular Electrophysiology (2013),  The GL Brown Lecture of the Physiological Society (2014), The Bohuslav Ostadal Lecture of The International Academy of Cardiovascular Sciences (2016), The Peter Harris Distinguished Scientist Award of The International Society for Heart Research (2017), and the Annual Review Prize Lecture of The Physiological Society (2017).  He has been elected a Fellow of the Academy of Medical Sciences and  to Honorary Fellowship of the Royal College of Physicians.  He serves on the editorial board of  Cell Calcium. He is the Editor in Chief of  The Journal of  Molecular and Cellular Cardiology. From 1992-2000, he was Chairman of the Editorial Board of The Journal of Physiology. He has been  International Secretary of the Physiological Society and Chair of the British Society for Cardiovascular Research.  He was Chair of the Working Group of Cardiac Cellular Electrophysiology of the European Society of Cardiology and has been President of both The Federation of European Physiological Societies (FEPS) and The International Society for Heart Research (European Section).  He chaired the International Scientific Programme Committe for the 2013 meeting of the International Union of Physiological Sciences (IUPS).  He has served on panels for the Research Assessment Exercise (RAE) in 2001 and 2008 and  REF2014.

Research interests

Cardiovascular disease is the major cause of death in the developed world. David Eisner’s research group is trying to understand the mechanisms that regulate the contraction of the heart under both normal and diseased conditions. The heart is composed of billions of cells (myocytes) and, in order for it to pump blood these cells must contract synchronously. Contraction is initiated by an increase of the amount of calcium in the cell. Most of this calcium is released from an intracellular store. This group has defined the mechanisms that control the amount of calcium in the store and thence the amount that can be released to activate contraction. Current work is focused on changes in the store content of calcium in disease conditions.

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