Drug Development: Influences on Regulatory Policies and Industrial Practices

Impact: Health impacts

Publications

  1. 2005
  2. Published

    CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

    Galetin, A., Ito, K., Hallifax, D. & Houston, J. B., Jul 2005, In : Journal of Pharmacology and Experimental Therapeutics. 314, 1, p. 180-190 10 p.

    Research output: Contribution to journalArticle

  3. Published

    Physiologically based pharmacokinetic modeling 1: Predicting the tissue distribution of moderate-to-strong bases

    Rodgers, T., Leahy, D. & Rowland, M., Jun 2005, In : Journal of Pharmaceutical Sciences. 94, 6, p. 1259-1276 17 p.

    Research output: Contribution to journalArticle

  4. 2004
  5. Published

    Physiologically Based Pharmacokinetics in Drug Development and Regulatory Science: A workshop report.

    Rowland, M., Balant, L. & Peck, C., 2004, AAPS Pharm. Sci.. Vol. 6 (1).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  6. 2001
  7. Published

    Optimizing drug development: Strategies to assess drug metabolism/transporter interaction potential - Toward a consensus

    Tucker, G. T., Houston, J. B. & Huang, S. M., 2001, In : Pharmaceutical Research. 18, 8, p. 1071-1080 9 p.

    Research output: Contribution to journalArticle

  8. 1999
  9. Published

    Quantitative characterization of therapeutic index: Application of mixed-effects modeling to evaluate oxybutynin dose-efficacy and dose-side effect relationships

    Gupta, S. K., Sathyan, G., Lindemulder, E. A., Ho, P. L., Sheiner, L. B. & Aarons, L., 1999, In : Clinical Pharmacology and Therapeutics. 65, 6, p. 672-684 12 p.

    Research output: Contribution to journalArticle

  10. 1994
  11. Published

    Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance’, Biochemical Pharmacology

    Houston, JB., 1994, In : Biochemical Pharmacology. 47, p. 1469-1479 10 p.

    Research output: Contribution to journalArticle

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