Division of Infection, Immunity & Respiratory Medicine

Publications

  1. 2019
  2. Published

    Inflammasome - independent role for NLRP3 in controlling innate anti - helminth immunity and tissue repair in the lung

    Chenery, A., Alhallaf, R., Agha, Z., Ajendra, J., Parkinson, J., Cooper, M. M., Chan, B. H. K., Eichenberger, R. M., Dent, L. A., Robertson, A. A. B., Kupz, A., Brough, D., Loukas, A., Sutherland, T., Allen, J. & Giacomin, P. R., 2019, In : Journal of Immunology.

    Research output: Contribution to journalArticle

  3. Published

    Interaction of a macrocycle with an aggregation-prone region of a monoclonal antibody

    Martinez Morales, M., Zalar, M., Sonzini, S., Golovanov, A., Van der Walle, C. & Derrick, J., 2019, In : Molecular Pharmaceutics.

    Research output: Contribution to journalArticle

  4. Published

    Inter-laboratory Analysis of Isavuconazole Plasma Concentration Assays Among European Laboratories

    Pea, F., Krause, R., Muller, C., Hennart, B., Richardson, M., Meinitzer, A., Wiesen, M. H. J., Wiktorowicz, T., Spickermann, J. & Santerre Henriksen, A., 2019, In : Therapeutic Drug Monitoring.

    Research output: Contribution to journalArticle

  5. Published

    Investigating the Safety of Capsaicin Cough Challenge in Severe Asthma

    Wang, R., Fowler, S., Niven, R., Ryan, D., Holt, K., Mitchell, J., Dockry, R., Al-Sheklly, B., Satia, I. & Smith, J., 2019, In : Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

    Research output: Contribution to journalLetter

  6. Published
  7. Published

    Laboratory cross-contamination of Mycobacterium tuberculosis: a systematic review and meta-analysis

    Barac, A., Karimzadeh-Esfahani, H., Pourostadi, M., Taghi Rahimi, M., Ahmadpour, E., Rashedi, J., Mahdavipoor, B., Samadi Kafil, H., Spotin, A., Hassen Abate, K., Mathioudakis, A. & Asgharzadeh, M., 2019, In : Lung.

    Research output: Contribution to journalArticle

  8. Published

    Life-threatening pulmonary interstitial lung disease complicating pediatric non-humoral immunodeficiencies

    Al Farsi, T., Hughes, S. M., Wynn, R., Cheesman, E., Rieux-Laucat, F., Latour, S., Picard, C., Hambleton, S. & Arkwright, P., 2019, In : The Journal of Allergy and Clinical Immunology: In Practice.

    Research output: Contribution to journalArticle

  9. Published

    Ligature-induced periodontitis induces systemic inflammation but does not alter acute outcome after stroke in mice

    O'Boyle, C., Haley, M. J., Lemarchand, E., Smith, C. J., Allan, S. M., Konkel, J. E. & Lawrence, C. B., 2019, In : International Journal of Stroke. p. 1747493019834191

    Research output: Contribution to journalArticle

  10. Published

    Lung Clearance Index in Detection of Post-Transplant Bronchiolitis Obliterans Syndrome

    Driskel, M., Horsley, A., Fretwell, L., Clayton, N. & Al-Aloul, M., 2019, In : European Respiratory Journal Open Research.

    Research output: Contribution to journalArticle

  11. Published

    Mapping histoplasmosis in South East Asia – implications for diagnosis in AIDS

    Baker, J., Sudradjat, F. S., Wahyuningsih, R. & Denning, D. W., 2019, In : Emerging Microbes & Infections. 8, 1, p. 1139-1145

    Research output: Contribution to journalArticle

  12. Published
  13. Published

    Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders

    Griffiths, W. J., Yutuc, E., Abdel-Khalik, J., Crick, P. J., Hearn, T., Dickson, A., Bigger, B. W., Hoi-Yee Wu, T., Goenka, A., Ghosh, A., Jones, S. A., Covey, D. F., Ory, D. S. & Wang, Y., 2019, In : Free Radical Biology and Medicine.

    Research output: Contribution to journalArticle

  14. Published

    Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study

    MASK study group, 2019, In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  15. Published

    Monthly variance in United Kingdom renal transplantation activity: a national retrospective cohort study

    Lowe, M., Maidstone, R., Poulton, K., Worthington, J., Durrington, H., Ray, D., van Dellen, D., Asderakis, A., Blaikley, J. & Augustine, T., 2019, In : BMJ Open.

    Research output: Contribution to journalArticle

  16. Published

    mSphere of Influence: the Importance of Metabolism for Pathogen Adaptation to Host-Imposed Stresses

    Amich Elias, J., 2019, In : mSphere.

    Research output: Contribution to journalComment/debate

  17. Published

    Neoantigen-directed immune escape in lung cancer evolution

    The TRACERx consortium, 2019, In : Nature. 567, 7749, p. 479-485 7 p.

    Research output: Contribution to journalArticle

  18. Published

    New understanding in the treatment of cough (NEUROCOUGH) ERS Clinical Research Collaboration: improving care and treatment for patients with cough

    NEUROCOUGH Clinical Research Collaboration, 2019, In : The European respiratory journal. 53, 5

    Research output: Contribution to journalEditorial

  19. Published

    Nocturnal asthma is affected by genetic interactions between RORA and NPSR1

    Curtin, J. & et al, 2019, In : Pediatric Pulmonology.

    Research output: Contribution to journalArticle

  20. Published

    Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours

    Youshani, A. S., Rowlston, S., O'Leary, C., Forte, G., Parker, H., Liao, A., Telfer, B., Williams, K., Kamaly-Asl, I. D. & Bigger, B. W., 2019, In : Journal of Neuroinflammation. 16, 1, 25.

    Research output: Contribution to journalArticle

  21. Published

    Novel contribution of epigenetic changes to nuclear dynamics

    Dreger, M., Madrazo, E., Hurlstone, A. & Redondo-Muñoz, J., 2019, In : Nucleus (Austin) . 10, 1, p. 42-47 6 p.

    Research output: Contribution to journalArticle

  22. Published

    Particles from the Echinococcus granulosus laminated layer inhibit CD40 upregulation in dendritic cells by interfering with Akt activation

    Pittini, Á., Martínez-acosta, Y. E., Casaravilla, C., Seoane, P. I., Rückerl, D., Quijano, C., Allen, J. E. & Díaz, A., 2019, In : Infection and immunity.

    Research output: Contribution to journalArticle

  23. Published

    Prognosis of COPD depends on severity of exacerbation history: A population-based analysis

    Çolak, Y., Afzal, S., Marott, J. L., Nordestgaard, B. G., Vestbo, J., Ingebrigtsen, T. S. & Lange, P., 2019, In : Respiratory Medicine. 155, p. 141-147

    Research output: Contribution to journalArticle

  24. Published

    Remotely monitored therapy and nitric oxide suppression identifies nonadherence in severe asthma

    Medical Research Council UK Refractory Asthma Stratification Programme (RASP-UK), 2019, In : American Journal of Respiratory and Critical Care Medicine . 199, 4, p. 454-464 11 p.

    Research output: Contribution to journalArticle

  25. Published

    Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

    Gurumurthy, C. B., O’brien, A. R., Quadros, R. M., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S. K., Beauchamp, M., Becker, K. A., Bernas, G., Brough, D., Carrillo-salinas, F., Chan, W., Chen, H., Dawson, R., Demambro, V., D’hont, J., Dibb, K. M., Eudy, J. D. & 93 others, Gan, L., Gao, J., Gonzales, A., Guntur, A. R., Guo, H., Harms, D. W., Harrington, A., Hentges, K. E., Humphreys, N., Imai, S., Ishii, H., Iwama, M., Jonasch, E., Karolak, M., Keavney, B., Khin, N., Konno, M., Kotani, Y., Kunihiro, Y., Lakshmanan, I., Larochelle, C., Lawrence, C. B., Li, L., Lindner, V., Liu, X., Lopez-castejon, G., Loudon, A., Lowe, J., Jerome-majewska, L. A., Matsusaka, T., Miura, H., Miyasaka, Y., Morpurgo, B., Motyl, K., Nabeshima, Y., Nakade, K., Nakashiba, T., Nakashima, K., Obata, Y., Ogiwara, S., Ouellet, M., Oxburgh, L., Piltz, S., Pinz, I., Ponnusamy, M. P., Ray, D., Redder, R. J., Rosen, C. J., Ross, N., Ruhe, M. T., Ryzhova, L., Salvador, A. M., Alam, S. S., Sedlacek, R., Sharma, K., Smith, C., Staes, K., Starrs, L., Sugiyama, F., Takahashi, S., Tanaka, T., Trafford, A. W., Uno, Y., Vanhoutte, L., Vanrockeghem, F., Willis, B. J., Wright, C. S., Yamauchi, Y., Yi, X., Yoshimi, K., Zhang, X., Zhang, Y., Ohtsuka, M., Das, S., Garry, D. J., Hochepied, T., Thomas, P., Parker-thornburg, J., Adamson, A. D., Yoshiki, A., Schmouth, J., Golovko, A., Thompson, W. R., Lloyd, K. C. K., Wood, J. A., Cowan, M., Mashimo, T., Mizuno, S., Zhu, H., Kasparek, P., Liaw, L., Miano, J. M. & Burgio, G., 2019, In : Genome biology. 20, 1

    Research output: Contribution to journalArticle

  26. Published

    Research highlights from the 2018 European Respiratory Society International Congress: airway disease

    Schleich, F., Bikov, A., Mathioudakis, A. G., Mcdonnell, M., Andersson, C., Bonini, M., Uller, L., Idzko, M., Singh, D., Lopez-campos, J. L., Bossios, A., Adcock, I. M., Usmani, O., Spanevello, A. & Bonvini, S. J., 2019, In : ERJ Open Research. 5, 1, p. 00225-2018

    Research output: Contribution to journalArticle

  27. Published

    Second round results from the Manchester ‘Lung Health Check’ community-based targeted lung cancer screening pilot

    Crosbie, P. A., Balata, H., Evison, M., Atack, M., Bayliss-brideaux, V., Colligan, D., Duerden, R., Eaglesfield, J., Edwards, T., Elton, P., Foster, J., Greaves, M., Hayler, G., Higgins, C., Howells, J., Irion, K., Karunaratne, D., Kelly, J., King, Z., Lyons, J. & 23 others, Manson, S., Mellor, S., Miller, D., Myerscough, A., Newton, T., O’leary, M., Pearson, R., Pickford, J., Sawyer, R., Screaton, N. J., Sharman, A., Simmons, M., Smith, E., Taylor, B., Taylor, S., Walsham, A., Watts, A., Whittaker, J., Yarnell, L., Threlfall, A., Barber, P. V., Tonge, J. & Booton, R., 2019, In : Thorax.

    Research output: Contribution to journalArticle

  28. Published

    Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases

    Fujino, N., Brand, O., Morgan, D., Fujimori, T., Grabiec, A., Jagger, C., Maciewicz, R., Yamada, M., Itakura, K., Sugiura, H., Ichinose, M. & Hussell, T., 2019, In : Journal of Experimental Medicine.

    Research output: Contribution to journalArticle

  29. Published

    Sex and intimacy in people with severe asthma: A qualitative study

    Holmes, L. J., Yorke, J. A., Dutton, C., Fowler, S. J. & Ryan, D., 2019, In : BMJ Open Respiratory Research. 6, 1, e000382.

    Research output: Contribution to journalArticle

  30. Published

    SIGN158: British guideline on the management of asthma

    SIGN Guideline development group, 2019, Scottish Intercollegiate Guidelines Network.

    Research output: Book/ReportCommissioned report

  31. Published

    Software for Dosage Individualization of Voriconazole: a Prospective Clinical Study

    Hope, W., Johnstone, G., Cicconi, S., Felton, T., Goodwin, J., Whalley, S., Santoyo-Castelazo, A., Ramos-Martin, V., Lestner, J., Credidio, L., Dane, A., Carr, D. F., Pirmohamed, M., Salim, R. & Neely, M., 2019, In : Antimicrobial Agents and Chemotherapy.

    Research output: Contribution to journalArticle

  32. Published

    Stable and Unstable Vortex Knots in Excitable Media

    Binysh, J., Whitfield, C. & Alexander, G. P., 2019, In : Physical Review E: covering statistical, nonlinear, biological, and soft matter physics. 99, 012211.

    Research output: Contribution to journalArticle

  33. Published

    Staphylococcus aureus internalized by skin keratinocytes evade antibiotic killing

    Al Kindi, A., Alkahtani, A. M., Nalubega, M., El Chami, C., O'Neill, C., Arkwright, P. & Pennock, J., 2019, In : Frontiers in Microbiology.

    Research output: Contribution to journalArticle

  34. Published

    Stress-induced changes in the lipid microenvironment of β- (1,3)-d-glucan synthase cause clinically important echinocandin resistance in Aspergillus fumigatus

    Satish, S., Jiménez-Ortigosa, C., Zhao, Y., Lee, M. H., Dolgov, E., Krüger, T., Park, S., Denning, D. W., Kniemeyer, O., Brakhage, A. A. & Perlin, D. S., 2019, In : mBio. 10, 3, e00779-19.

    Research output: Contribution to journalArticle

  35. Published
  36. Published

    Systematic review on women's values and preferences concerning breast cancer screening and diagnostic services

    Mathioudakis, A. G., Salakari, M., Pylkkanen, L., Saz-Parkinson, Z., Bramesfeld, A., Deandrea, S., Lerda, D., Neamtiu, L., Pardo-Hernandez, H., Solà, I. & Alonso-Coello, P., 2019, In : Psycho-oncology.

    Research output: Contribution to journalArticle

  37. Published

    T lymphocyte phenotype of contact allergic patients: experience with nickel and p-phenylenediamine

    Wicks, K., Stretton, C., Popple, A., Beresford, L., Williams, J., Maxwell, G., Gosling, J. P., Kimber, I. & Dearman, R. J., 2019, In : Contact dermatitis.

    Research output: Contribution to journalArticle

  38. Published

    TGFβ-activation by dendritic cells drives Th17 induction and intestinal contractility and augments the expulsion of the parasite Trichinella spiralis in mice

    Steel, N., Faniyi, A. A., Rahman, S., Swietlik, S., Czajkowska, B., Chan, B. T., Hardgrave, A., Steel, A., Sparwasser, T., Assas, M., Grencis, R., Travis, M. & Worthington, J. J., 2019, In : PL o S Pathogens.

    Research output: Contribution to journalArticle

  39. Published

    The C-terminal dimerization domain of the respiratory mucin MUC5B functions in mucin stability and intracellular packaging before secretion

    Ridley, C., Lockhart-cairns, M. P., Collins, R. F., Jowitt, T. A., Subramani, D. B., Kesimer, M., Baldock, C. & Thornton, D. J., 2019, In : Journal of Biological Chemistry. p. jbc.RA119.010771

    Research output: Contribution to journalArticle

  40. Published

    The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation

    Svedberg, F. R., Brown, S. L., Krauss, M. Z., Campbell, L., Sharpe, C., Clausen, M., Howell, G. J., Clark, H., Madsen, J., Evans, C. M., Sutherland, T. E., Ivens, A. C., Thornton, D. J., Grencis, R. K., Hussell, T., Cunoosamy, D. M., Cook, P. C. & MacDonald, A. S., 2019, In : Nature Immunology.

    Research output: Contribution to journalArticle

  41. Published

    The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

    Bancroft, A., Levy, C., Jowitt, T., Hayes, K., Thompson, S., Mckenzie, E., Ball, M., Dubaissi, E., France, A., Bellina, B., Sharpe, C., Mironov, A., Brown, S., Cook, P., MacDonald, A., Thornton, D. & Grencis, R., 2019, In : Nature Communications.

    Research output: Contribution to journalArticle

  42. Published

    The pathology of small airways disease in COPD: Historical aspects and future directions

    Higham, A., Quinn, A. M., Cançado, J. E. D. & Singh, D., 2019, In : Respiratory research. 20, 1, 49.

    Research output: Contribution to journalReview article

  43. Published

    The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions

    Fox, A., Bird, J. A., Fiocchi, A., Knol, J., Meyer, R., Salminen, S., Sitang, G., Szajewska, H. & Papadopoulos, N., 2019, In : World Allergy Organization Journal. 12, 5, 100034.

    Research output: Contribution to journalReview article

  44. Published

    The role of measuring exhaled breath biomarkers in sarcoidosis: A systematic review

    Terrington, D., Hayton, C., Fowler, S. J. & Fraser, W., 2019, In : Journal of Breath Research.

    Research output: Contribution to journalArticle

  45. Published

    The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

    Tapia, V. S., Daniels, M. J. D., Palazón-riquelme, P., Dewhurst, M., Luheshi, N. M., Rivers-auty, J., Green, J., Redondo-castro, E., Kaldis, P., Lopez-castejon, G. & Brough, D., 2019, In : Journal of Biological Chemistry. p. jbc.RA119.008009

    Research output: Contribution to journalArticle

  46. Published

    Top Ten Research Priorities for Detecting Cancer Early

    Renehan, A., Crosbie, E., Crosbie, P. & Detecting Cancer Early PSP steering group, 2019, In : The Lancet Public Health.

    Research output: Contribution to journalArticle

  47. Published

    Transfusion-transmitted Malaria: A Systematic Review and Meta-Analysis

    Ahmadpour, E., Foroutan-rad, M., Majidiani, H., Moghaddam, S. M., Hatam-nahavandi, K., Hosseini, S., Rahimi, M. T., Barac, A., Rubino, S., Zarean, M., Mathioudakis, A. G. & Cevik, M., 2019, In : Open Forum Infectious Diseases.

    Research output: Contribution to journalArticle

  48. Published

    Treatment response to indacaterol/glycopyrronium versus salmeterol/fluticasone in exacerbating COPD patients by gender: A post-hoc analysis in the FLAME study 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine and Haematology

    Wedzicha, J. A., Singh, D., Tsiligianni, I., Jenkins, C., Fucile, S., Fogel, R., Shen, S., Goyal, P., Mezzi, K. & Kostikas, K., 2019, In : Respiratory research. 20, 1, 4.

    Research output: Contribution to journalArticle

  49. Published

    Trichosporon japonicum fungemia and ventricular assist device infection in an immunocompetent patient

    Bongomin, F., Otu, A. A., Calisti, A., Richardson, M., Barnard, J., Venkateswaran, R. & Vergidis, P., 2019, In : Open Forum Infectious Diseases .

    Research output: Contribution to journalArticle

  50. Published

    Type I interferons provide additive signals for murine regulatory B cell induction by Schistosoma mansoni eggs

    Obieglo, K., Costain, A., Webb, L. M., Ozir-Fazalalikhan, A., Brown, S. L., MacDonald, A. S. & Smits, H. H., 2019, In : European journal of immunology.

    Research output: Contribution to journalArticle

  51. Published

    Understanding and Enhancing Sepsis Survivorship: Priorities for Research and Practice

    Dark, P. & et al., 2019, In : American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticle

  52. Published

    Unmet Needs in Severe Asthma Subtyping and Precision Medicine Trials: Bridging Clinical and Patient Perspectives

    Siddiqui, S., Denlinger, L. C., Fowler, S. J., Akuthota, P., Shaw, D. E., Heaney, L. G., Brown, L., Castro, M., Winders, T. A., Kraft, M., Wagers, S., Peters, M. C., Pavord, I. D., Walker, S. & Jarjour, N. N., 2019, In : American Journal of Respiratory and Critical Care Medicine .

    Research output: Contribution to journalArticle

  53. Published

    Vertebral, pelvic and hip fracture risk in adults with severe atopic dermatitis

    Arkwright, P. D. & Mughal, M. Z., 2019, In : Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  54. Published

    Was the implementation strategy of the ProACT trial adequately proactive?

    Mathioudakis, A. & Vestbo, J., 2019, In : Breathe. 15, p. 77-80 3 p.

    Research output: Contribution to journalArticle

  55. Published

    When to use single-inhaler triple therapy in COPD: A practical approach for primary care health care professionals

    Gaduzo, S., McGovern, V., Roberts, J., Scullion, J. E. & Singh, D., 2019, In : International Journal of COPD. 14, p. 391-401 11 p.

    Research output: Contribution to journalArticle

  56. Published

    β2-Adrenergic genotypes and risk of severe exacerbations in COPD: a prospective cohort study

    Ingebrigtsen, T. S., Vestbo, J., Rode, L., Marott, J. L., Lange, P. & Nordestgaard, B. G., 2019, In : Thorax. p. thoraxjnl-2018-212340

    Research output: Contribution to journalArticle

  57. 2018
  58. Published

    Time of Day Affects Eosinophil Biomarkers in Asthma: Implications for Diagnosis and treatment

    Durrington, H. J., Gioan-tavernier, G. O., Maidstone, R. J., Krakowiak, K., Loudon, A. S. I., Blaikley, J. F., Fowler, S. J., Singh, D., Simpson, A. & Ray, D. W., 15 Dec 2018, In : American Journal of Respiratory and Critical Care Medicine . 13 p., 30156881.

    Research output: Contribution to journalArticle

  59. Published

    The chemokine receptor CXCR2 contributes to murine adipocyte development

    Dyer, D. P., Nebot, J. B., Kelly, C. J., Medina-Ruiz, L., Schuette, F. & Graham, G. J., 5 Dec 2018, In : Journal of leukocyte biology.

    Research output: Contribution to journalArticle

  60. Published

    Advances in Imaging and Automated Quantification of Malignant Pulmonary Diseases: A State-of-the-Art Review

    Hochhegger, B., Zanon, M., Altmayer, S., Pacini, G. S., Balbinot, F., Francisco, M. Z., Dalla Costa, R., Watte, G., Santos, M. K., Barros, M. C., Penha, D., Irion, K. & Marchiori, E., 1 Dec 2018, In : Lung. 196, 6, p. 633-642

    Research output: Contribution to journalArticle

  61. Published

    Distinct Roles for CD4+ Foxp3+ Regulatory T Cells and IL-10-Mediated Immunoregulatory Mechanisms during Experimental Visceral Leishmaniasis Caused by Leishmania donovani

    Bunn, P. T., Montes de Oca, M., de Labastida Rivera, F., Kumar, R., Ng, S. S., Edwards, C. L., Faleiro, R. J., Sheel, M., Amante, F. H., Frame, T. C. M., Muller, W., Haque, A., Uzonna, J. E., Hill, G. R. & Engwerda, C. R., 1 Dec 2018, In : Journal of immunology (Baltimore, Md. : 1950). 201, 11, p. 3362-3372

    Research output: Contribution to journalArticle

  62. Published

    The impact of a diagnostics-driven antifungal stewardship programme in a UK tertiary referral teaching hospital

    Rautemaa-Richardson, R., Rautemaa, V., Al-Wathiqi, F., Moore, CB., Craig, L., Felton, T. & Muldoon, E., 1 Dec 2018, In : Journal of Antimicrobial Chemotherapy. 73, 12, p. 3488-3495 7 p.

    Research output: Contribution to journalArticle

  63. Published

    Dropping acid: why is cystic fibrosis mucus abnormal?

    Rubin, B. K. & Thornton, D. J., Dec 2018, In : European Respiratory Journal. 52, 6, 1802057.

    Research output: Contribution to journalEditorial

  64. Published

    Late-onset isavuconazole-induced liver injury

    Bongomin, F., Rodriguez-goncer, I., Lorden, C., Otu, A. & Bazaz, R., Dec 2018, In : Medical Mycology Case Reports. 22, p. 11-13

    Research output: Contribution to journalArticle

  65. Published

    Leukocyte migration and inflammatory disease: the collaboration between endothelial sugars and chemokines

    Dyer, D. P., Salanga, C. L., Migliorini, E., Thakar, D., Kawamura, T., Graham, G., Richter, R. P. & Handel, T. M., Dec 2018, In : International Journal of Experimental Pathology . 99, 6, p. A60-A60

    Research output: Contribution to journalMeeting Abstract

  66. Published

    The cost-effectiveness of the Manchester ‘lung health checks’, a community-based lung cancer low-dose CT screening pilot

    Hinde, S., Crilly, T., Balata, H., Bartlett, R., Crilly, J., Barber, P., Threlfall, A., Tonge, J., Booton, R. & Crosbie, P. A., Dec 2018, In : Lung Cancer. 126, p. 119-124 6 p.

    Research output: Contribution to journalArticle

  67. Accepted/In press

    Innate immune cell suppression and the link with secondary lung bacterial pneumonia

    Morgan, D., Casulli, J., Chew, C., Connolly, E., Lui, S., Brand, O., Rahman, R., Jagger, C. & Hussell, T., 30 Nov 2018, (Accepted/In press) In : Frontiers in Immunology.

    Research output: Contribution to journalArticle

  68. Published

    Bronchiolitis needs a revisit: Distinguishing between virus entities and their treatments

    EAACI Task Force on Clinical Practice Recommendations on Preschool Wheeze, 25 Nov 2018, In : Allergy: European Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  69. Published

    Detection of genuine grass pollen sensitization in children by skin testing with a recombinant grass pollen hybrid

    Douladiris, N., Garib, V., Focke-Tejkl, M., Valenta, R., Papadopoulos, N. G. & Linhart, B., 25 Nov 2018, In : Pediatric Allergy and Immunology.

    Research output: Contribution to journalArticle

  70. Published

    Methicillin-resistant Staphylococcus aureus alters cell wall glycosylation to evade immunity

    Gerlach, D., Guo, Y., De Castro, C., Kim, S-H., Schlatterer, K., Xu, F-F., Pereira, C., Seeberger, P. H., Ali, S., Codée, J., Sirisarn, W., Schulte, B., Wolz, C., Larsen, J., Molinaro, A., Lee, B. L., Xia, G., Stehle, T. & Peschel, A., 21 Nov 2018, In : Nature. 563, 7733, p. 705-709 5 p.

    Research output: Contribution to journalArticle

  71. Published

    A Disintegrin and A Metalloproteinase Domain-8 (ADAM8): A Novel Protective Proteinase in COPD

    Polverino, F., Rojas-Quintero, J., Wang, X., Petersen, H., Zhang, L., Gai, X., Higham, A., Zhang, D., Gupta, K., Rout, A., Yambayev, I., Pinto-Plata, V., Sholl, L. M., Cunoosamy, D., Celli, B. R., Goldring, J., Singh, D., Tesfaigzi, Y., Wedzicha, J., Olsson, H. & 1 others, Owen, C. A., 15 Nov 2018, In : American Journal of Respiratory and Critical Care Medicine. 198, 10, p. rccm.201707-1331OC

    Research output: Contribution to journalArticle

  72. Published

    Pediatric asthma: An unmet need for more effective, focused treatments

    Papadopoulos, N. G., Čustović, A., Cabana, M. D., Dell, S. D., Deschildre, A., Hedlin, G., Hossny, E., Le Souëf, P., Matricardi, P. M., Nieto, A., Phipatanakul, W., Pitrez, P. M., Pohunek, P., Gavornikova, M., Jaumont, X. & Price, D. B., 15 Nov 2018, In : Pediatric Allergy and Immunology.

    Research output: Contribution to journalArticle

  73. Published
  74. Published

    Non-directed bronchial lavage is a safe method for sampling the respiratory tract in critically ill patient

    Bonvento, B. V., Rooney, J. A., Columb, M. O., McGrath, B. A., Bentley, A. M. & Felton, T. W., 13 Nov 2018, In : Journal of the Intensive Care Society.

    Research output: Contribution to journalArticle

  75. Published

    Trajectories of childhood immune development and respiratory health relevant to asthma and allergy

    Tang, H. H., Teo, S. M., Belgrave, D. C., Evans, M. D., Jackson, D. J., Brozynska, M., Kusel, M. M., Johnston, S. L., Gern, J. E., Lemanske, R. F., Simpson, A., Custovic, A., Sly, P. D., Holt, P. G., Holt, K. E. & Inouye, M., 7 Nov 2018, In : eLife. 7

    Research output: Contribution to journalArticle

  76. Published

    Intestinal helminth infection promotes IL-5- and CD4+ T cell-dependent immunity in the lung against migrating parasites.

    Filbey, K., 6 Nov 2018, In : Mucosal Immunology.

    Research output: Contribution to journalArticle

  77. Published

    Human monocytes and macrophages regulate immune tolerance via integrin αvβ8–mediated TGFβ activation

    Kelly, A., Gunaltay, S., Mcentee, C. P., Shuttleworth, E. E., Smedley, C., Houston, S. A., Fenton, T. M., Levison, S., Mann, E. R. & Travis, M. A., 5 Nov 2018, In : The Journal of experimental medicine. 215, 11

    Research output: Contribution to journalArticle

  78. Published

    Assessment of atopic dermatitis as a risk factor for chronic spontaneous urticaria in a pediatric population

    Kitsioulis, N. A., Papadopoulos, N. G., Kostoudi, S., Manousakis, E., Douladiris, N. & Xepapadaki, P., 1 Nov 2018, In : Allergy and Asthma Proceedings. 39, 6, p. 445-448 4 p.

    Research output: Contribution to journalArticle

  79. Published

    Diagnostic performance of clinical characteristics to detect airflow limitation in people living with HIV and in uninfected controls

    Ronit, A., Benfield, T., Mocroft, A., Gerstoft, J., Nordestgaard, B., Vestbo, J. & Nielsen, S., 1 Nov 2018, In : HIV Medicine. 19, 10, p. 751-755

    Research output: Contribution to journalArticle

  80. Published

    Global burden of recurrent vulvovaginal candidiasis: a systematic review

    Denning, D., Kneale, M., Sobel, J. D. & Rautemaa-Richardson, R., 1 Nov 2018, In : The Lancet Infectious Diseases. 18, 11

    Research output: Contribution to journalArticle

  81. Published

    Whole exome sequencing analysis in severe chronic obstructive pulmonary disease

    Qiao, D., Ameli, A., Prokopenko, D., Chen, H., Kho, A. T., Parker, M. M., Morrow, J., Hobbs, B. D., Liu, Y., Beaty, T. H., Crapo, J. D., Barnes, K. C., Nickerson, D. A., Bamshad, M., Hersh, C. P., Lomas, D. A., Agusti, A., Make, B. J., Calverley, P. M. A., Donner, C. F. & 12 others, Wouters, E. F., Vestbo, J., Paré, P. D., Levy, R. D., Rennard, S. I., Tal-Singer, R., Spitz, M. R., Sharma, A., Ruczinski, I., Lange, C., Silverman, E. K. & Cho, M. H., 1 Nov 2018, In : Human Molecular Genetics. 27, 21, p. 3801-3812 12 p.

    Research output: Contribution to journalArticle

  82. Published

    Multidisciplinary guidelines for the management of paediatric tracheostomy emergencies

    Doherty, C., Atkinson, D., Moore, J., Monks, S., Bowler, M., Bruce, I. A., Bateman, N., Wyatt, M., Russell, J., Perkins, R. & McGrath, B. A., Nov 2018, In : Anaesthesia Anaesthe. 73, 11, p. 1400-1417

    Research output: Contribution to journalArticle

  83. Published

    Predicting survival following surgical resection of lung cancer using clinical and pathological variables: The development and validation of the LNC-PATH score

    Balata, H., Foden, P., Edwards, T., Chaturvedi, A., Elshafi, M., Tempowski, A., Teng, B., Whittemore, P., Blyth, K. G., Kidd, A., Ellames, D., Flint, L. A., Robson, J., Teh, E., Jones, R., Batchelor, T., Crosbie, P., Booton, R. & Evison, M., Nov 2018, In : Lung Cancer. 125, p. 29-34

    Research output: Contribution to journalArticle

  84. Published

    Methodological considerations for large-scale breath analysis studies: lessons from the U-BIOPRED severe asthma project

    the U-BIOPRED study group, 30 Oct 2018, In : Journal of Breath Research. 13, 1

    Research output: Contribution to journalArticle

  85. Published

    VX-659–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles

    Davies, J. C., Moskowitz, S. M., Brown, C., Horsley, A., Mall, M. A., Mckone, E. F., Plant, B. J., Prais, D., Ramsey, B. W., Taylor-cousar, J. L., Tullis, E., Uluer, A., Mckee, C. M., Robertson, S., Shilling, R. A., Simard, C., Van Goor, F., Waltz, D., Xuan, F., Young, T. & 1 others, Rowe, S. M., 25 Oct 2018, In : New England Journal Of Medicine. 379, 17, p. 1599-1611 12 p.

    Research output: Contribution to journalArticle

  86. Published

    Oxygen therapy for medical patients

    Horner, D. & O'Driscoll, R., 24 Oct 2018, In : BMJ (Clinical Research Edition). 363, p. k4436

    Research output: Contribution to journalEditorial

  87. Published

    Amphiregulin producing γδ T cells are vital for safeguarding oral barrier immune homeostasis

    Krishnan, S., Prise, I., Wemyss, K., Schenck, L., Bridgeman, H., Mcclure, F., Zangerle Murray, T., O'Boyle, C., Barbera, T., Mahmood, F., Bowdish, D. M. E., Zaiss, D. M., Grainger, J. & Konkel, J., 16 Oct 2018, In : Proceedings of the National Academy of Sciences. 115, 42, p. 10738-10743 6 p.

    Research output: Contribution to journalArticle

  88. Published

    Drug-Induced Interstitial Lung Disease: A Systematic Review

    Skeoch, S., Weatherley, N., Swift, A., Oldroyd, A., Johns, C., Hayton, C., Giollo, A., Wild, J., Waterton, J., Buch, M., Linton, K., Bruce, I., Leonard, C., Bianchi, S. & Chaudhuri, N., 15 Oct 2018, In : Journal of Clinical Medicine. 7, 10, p. 356

    Research output: Contribution to journalArticle

  89. Published

    A mixed-methods study of the management of hearing loss associated with otitis media with effusion in children with Down syndrome

    Hall, A., Pryce, H., Bruce, I. A., Callery, P., Lakhanpaul, M. & Schilder, A. G. M., 8 Oct 2018, In : Clinical Otolaryngology.

    Research output: Contribution to journalArticle

  90. Published

    Chloride regulates dynamic NLRP3-dependent ASC oligomerisation and inflammasome priming

    Green, J., Yu, S., Martín-Sánchez, F., Pelegrin, P., Lopez-Castejon, G., Lawrence, C. B. & Brough, D., 2 Oct 2018, In : Proceedings of the National Academy of Sciences. 115, 40, p. E9371-E9380

    Research output: Contribution to journalArticle

  91. Published

    LABA/LAMA Fixed Dose Combination in Chronic Obstructive Pulmonary Disease: The Impact on Health-Related Quality of Life

    Labor, M., Braido, F., Bikov, A., Lahousse, L., Rogliani, P. & Baiardini, I., 1 Oct 2018, In : Respiration. 96, 4, p. 370-381

    Research output: Contribution to journalArticle

  92. Published

    Brain-Derived Neurotrophic Factor, Insulin Like Growth Factor -1 and Inflammatory Cytokines Responses to Continuous and Intermittent Exercise in Patients with Type 1 Diabetes.

    Zebrowska, A., Hall, B., Maszczyk, A., Banas, R. & Urban, J., Oct 2018, In : Diabetes Research and Clinical Practice. 144, p. 126-136

    Research output: Contribution to journalArticle

  93. Published
  94. Published

    Mucins: the frontline defence of the lung

    Ridley, C. & Thornton, D., Oct 2018, In : Biochemical Society Transactions. 46, 5, p. 1099-1106

    Research output: Contribution to journalArticle

  95. Published

    Ribonucleotide excision repair is essential to prevent squamous cell carcinoma of the skin

    Hiller, B., Hoppe, A., Haase, C., Hiller, C., Schubert, N., Müller, W., Reijns, M. A. M., Kunkel, T. A., Wenzel, J., Behrendt, R. & Roers, A., Oct 2018, In : Cancer Research. 78, 20

    Research output: Contribution to journalArticle

  96. Published

    Targeted lung cancer screening selects individuals at high risk of cardiovascular disease.

    Balata, H., Knight, S., Barber, P., Colligan, D., Crosbie, E., Duerdan, R., Elton, P., Evison, M., Greaves, M., Howells, J., Irion, K., Karunaratne, D., Kirwan, M., Macnab, A., Mellor, S., Miller, C., Newton, T., Novasio, J., Sawyer, R., Sharman, A. & 10 others, Slevin, K., Smith, E., Taylor, B., Taylor, S., Tonge, J., Walsham, A., Waplington, S., Whittaker, J., Booton, R. & Crosbie, P., Oct 2018, In : Lung Cancer. 124, p. 148-153 6 p.

    Research output: Contribution to journalArticle

  97. Published

    Nintedanib in the management of idiopathic pulmonary fibrosis: clinical trial evidence and real-world experience

    Rivera-Ortega, P., Hayton, C., Blaikley, J., Leonard, C. & Chaudhuri, N., 27 Sep 2018, In : Therapeutic Advances in Respiratory Disease. 12, p. 1753466618800618

    Research output: Contribution to journalArticle

  98. Published

    Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo

    Vickers, C. F., Silva, A. P. G., Chakraborty, A., Fernandez, P., Kurepina, N., Saville, C., Naranjo, Y., Pons, M., Schnettger, L. S., Gutierrez, M. G., Park, S., Kreiswith, B. N., Perlin, D. S., Thomas, E. J., Cavet, J. S. & Tabernero, L., 27 Sep 2018, In : Journal of Medicinal Chemistry. 61, 18, p. 8337-8352 16 p.

    Research output: Contribution to journalArticle

  99. Published
  100. Published

    Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort

    U-BIOPRED Study Group, 21 Sep 2018, In : PLoS ONE. 13, 9, p. e0203874

    Research output: Contribution to journalArticle

  101. Published

    Lung colonization by Aspergillus fumigatus is controlled by ZNF77

    Gago, S., Overton, N., Ben Ghazzi, N., Novak Frazer, L., Read, N., Denning, D. W. & Bowyer, P., 20 Sep 2018, In : Nature Communications. 9, 3835.

    Research output: Contribution to journalArticle

  102. Published

    Substrate accumulation and extracellular matrix remodelling promote persistent upper airway disease in mucopolysaccharidosis patients on enzyme replacement therapy

    Pal, A. R., Mercer, J., Jones, S. A., Bruce, I. A., Bigger, B. W. & Dardis, A. (ed.), 18 Sep 2018, In : PLoS ONE. 13, 9, p. e0203216

    Research output: Contribution to journalArticle

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