Division of Infection, Immunity & Respiratory Medicine

Publications

  1. 2019
  2. Published

    Interventions to improve communication in mechanically ventilated patients: a review

    Talbot, S. & McGrath, B. A., Mar 2019, In : British Journal of Anaesthesia. 122, 3, p. E49-E50

    Research output: Contribution to journalMeeting Abstract

  3. Published

    Soluble Urokinase-Type Plasminogen Activator Receptor and Arterial Stiffness in Patients with COPD

    Böcskei, R. M., Benczúr, B., Losonczy, G., Illyés, M., Cziráki, A., Müller, V., Bohács, A. & Bikov, A., 28 Feb 2019, In : Lung.

    Research output: Contribution to journalArticle

  4. Accepted/In press

    A novel glycopolymer improves abnormal cystic fibrosis mucus

    Fernanadez-Petty, C. M., Hughes, G., Bowers, H. L., Watson, J. D., Rosen, B. H., Townsend, S. M., Santos, C., Ridley, C., Chu, K. K., Birket, S. E., Li, Y., Leung, H. M., Mazur, M., Garcia, B. A., Apak Evans, T. I., Falk Libby, E., Hathorne, H., Hanes, J., Tearney, G. J., Clancy, J. P. & 6 others, Engelhardt, J. F., Swords, W. E., Thornton, D., Wiesmann, W. P., Baker, S. M. & Rowe, S. M., 27 Feb 2019, (Accepted/In press) In : Journal of Clinical Investigation Insight.

    Research output: Contribution to journalArticle

  5. Published

    Detection of local allergic rhinitis in children with chronic, difficult-to-treat, non-allergic rhinitis using multiple nasal provocation tests

    Tsilochristou, O., Kyriakakou, M., Manolaraki, I., Lakoumentas, J., Tiligada, E., Maragkoudakis, P., Douladiris, N. & Papadopoulos, N. G., 26 Feb 2019, In : Pediatric Allergy and Immunology.

    Research output: Contribution to journalArticle

  6. Published

    Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity

    Martínez-López, M., Iborra, S., Conde-Garrosa, R., Mastrangelo, A., Danne, C., Mann, E. R., Reid, D. M., Gaboriau-Routhiau, V., Chaparro, M., Lorenzo, M. P., Minnerup, L., Saz-Leal, P., Slack, E., Kemp, B., Gisbert, J. P., Dzionek, A., Robinson, M. J., Rupérez, F. J., Cerf-Bensussan, N., Brown, G. D. & 3 others, Bernardo, D., LeibundGut-Landmann, S. & Sancho, D., 19 Feb 2019, In : Immunity. 50, 2, p. 446-461.e9

    Research output: Contribution to journalArticle

  7. Published

    Using research to prepare for outbreaks of severe acute respiratory infection

    Bentley, A., 13 Feb 2019, In : BMJ Global Health.

    Research output: Contribution to journalArticle

  8. Published

    Effect of Sex on Group 2 Innate Lymphoid Cells in the Airways of Mild and Severe Asthmatics

    Aw, M., Nair, P., Salter, B., Chen, R., Machida, K., Inman, M., O'Byrne, P. M., Gauvreau, G. M. & Sehmi, R., 11 Feb 2019, In : Allergy.

    Research output: Contribution to journalArticle

  9. Published

    Comparison of the effect of beclometasone/formoterol in asthma patients after methacholine-induced bronchoconstriction: A noninferiority study using metered dose vs. dry powder inhaler

    Singh, D., van den Berg, F., Leaker, B., Corradi, M., Jabbal, S., Collarini, S., Mongelli, V., Santoro, L., Piccinno, A., Biondaro, S. & Lipworth, B., 3 Feb 2019, In : British Journal of Clinical Pharmacology.

    Research output: Contribution to journalArticle

  10. Published

    Physiological, hyaluronan-selected intracytoplasmic sperm injection for infertility treatment (HABSelect): a parallel, two-group, randomised trial

    Miller, D., Pavitt, S., Sharma, V., Forbes, G., Hooper, R., Bhattacharya, S., Kirkman-Brown, J., Coomarasamy, A., Lewis, S., Cutting, R., Brison, D., Pacey, A., West, R., Brian, K., Griffin, D. & Khalaf, Y., 2 Feb 2019, In : Lancet (London, England). 393, 10170, p. 416-422 7 p.

    Research output: Contribution to journalArticle

  11. Published

    A nonmyeloablative chimeric mouse model accurately defines microglia and macrophage contribution in glioma

    Yu, K., Youshani, A. S., Wilkinson, F. L., O'Leary, C., Cook, P., Laaniste, L., Liao, A., Mosses, D., Waugh, C., Shorrock, H., Pathmanaban, O., Macdonald, A., Kamaly-Asl, I., Roncaroli, F. & Bigger, B. W., 1 Feb 2019, In : Neuropathology and Applied Neurobiology. 45, 2, p. 119-140 22 p.

    Research output: Contribution to journalArticle

  12. Published

    Benefit and safety of fluticasone furoate/vilanterol in the Salford Lung Study in chronic obstructive pulmonary disease (SLS COPD) according to baseline patient characteristics and treatment subgroups

    Bakerly, N. D., Woodcock, A., Collier, S., Leather, D. A., New, J. P., Crawford, J., Harvey, C., Vestbo, J. & Boucot, I., 1 Feb 2019, In : Respiratory Medicine. 147, p. 58-65 8 p.

    Research output: Contribution to journalArticle

  13. Published

    Individual risk factors predictive of venous thromboembolism in patients with temporary lower limb immobilization due to injury: a systematic review

    Horner, D., Pandor, A., Goodacre, S., Clowes, M. & Hunt, B. J., 1 Feb 2019, In : Journal of thrombosis and haemostasis : JTH. 17, 2, p. 329-344 16 p.

    Research output: Contribution to journalArticle

  14. Published

    Pulmonary cryptococcosis: A review of pathobiology and clinical aspects

    Setianingrum, F., Rautemaa-richardson, R. & Denning, D., 1 Feb 2019, In : Medical Mycology . 57, 2, p. 133-150

    Research output: Contribution to journalArticle

  15. Published

    Interleukin-1 mediates ischaemic brain injury via distinct actions on endothelial cells and cholinergic neurons

    Wong, R., Lénárt, N., Hill, L., Toms, L., Martinecz, B., Császár, E., Nyiri, G., Papaemmanouil, A., Waisman, A., Muller, W., Schwaninger, M., Rothwell, N., Francis, S., Pinteaux, E., Denes, A. & Allan, S., Feb 2019, In : Brain, Behavior, and Immunity. 76

    Research output: Contribution to journalArticle

  16. Published

    Multidisciplinary Tracheostomy Care: How Collaboratives Drive Quality Improvement

    Bedwell, J. R., Pandian, V., Roberson, D. W., McGrath, B. A., Cameron, T. S. & Brenner, M. J., Feb 2019, In : Otolaryngologic Clinics of North America. 52, 1, p. 135-147 13 p.

    Research output: Contribution to journalArticle

  17. Published

    The interleukin-13 paradox in asthma: effective biology, ineffective biologicals

    Nair, P. & O'Byrne, P. M., Feb 2019, In : The European respiratory journal. 53, 2

    Research output: Contribution to journalArticle

  18. Published

    Intermittent prophylactic antibiotics for bronchiectasis (Review)

    Spencer, S., Donovan, T., Mathioudakis, A., McDonnell, M. J., Tsang, A. & Pilkington, G., 31 Jan 2019, In : Cochrane Database of Systematic Reviews.

    Research output: Contribution to journalArticle

  19. Published

    Decision-analysis modelling of the effects of thromboprophylaxis for people with lower limb immobilisation for injury

    Davis, S., Goodacre, S., Pandor, A., Horner, D., Stevens, J. W., de Wit, K. & Hunt, B. J., 29 Jan 2019, In : British Journal of Haematology. 186, 1, p. 166-168 3 p.

    Research output: Contribution to journalLetter

  20. Published

    Chronic inflammation in response to injury: retention of myeloid cells in injured tissue is driven by myeloid cell-intrinsic factors

    Torbica, T., Wicks, K., Umehara, T., Gungordu, L., Alrdahe, S., Wemyss, K., Grainger, J. & Mace, K., 28 Jan 2019, In : The Journal of Investigative Dermatology.

    Research output: Contribution to journalArticle

  21. Published

    Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis

    Koliaraki, V., Chalkidi, N., Henriques, A., Tzaferis, C., Polykratis, A., Waisman, A., Muller, W., Hackam, D. J., Pasparakis, M. & Kollias, G., 15 Jan 2019, In : Cell Reports. 26, 3, p. 536-545.e4

    Research output: Contribution to journalArticle

  22. Published
  23. E-pub ahead of print

    Exclusive dependence of IL-10Rα signalling on intestinal microbiota homeostasis and control of whipworm infection

    Sanger Mouse Genetics Project, 14 Jan 2019, In : PLoS Pathogens. 15, 1, p. e1007265

    Research output: Contribution to journalArticle

  24. Published

    Breath biomarkers in idiopathic pulmonary fibrosis: a systematic review

    Hayton, C., Terrington, D., Chaudhuri, N., Leonard, C. & Fowler, S. J., 11 Jan 2019, In : Respiratory research. 20, 1, p. 7

    Research output: Contribution to journalReview article

  25. Published

    IL-10 signalling in dendritic cells is required for tolerance induction in a murine model of allergic airway inflammation

    Dolch, A., Kunz, S., Dorn, B., Alessandrini, F., Muller, W., Jack, R. S., Martin, S. F., Roers, A. & Jakob, T., 3 Jan 2019, In : European journal of immunology.

    Research output: Contribution to journalArticle

  26. Published

    Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

    Shrine, N., Portelli, M. A., John, C., Soler Artigas, M., Bennett, N., Hall, R., Lewis, J., Henry, A. P., Billington, C. K., Ahmad, A., Packer, R. J., Shaw, D., Pogson, Z. E. K., Fogarty, A., McKeever, T. M., Singapuri, A., Heaney, L. G., Mansur, A. H., Chaudhuri, R., Thomson, N. C. & 23 others, Holloway, J. W., Lockett, G. A., Howarth, P. H., Djukanovic, R., Hankinson, J., Niven, R., Simpson, A., Chung, K. F., Sterk, P. J., Blakey, J. D., Adcock, I. M., Hu, S., Guo, Y., Obeidat, M., Sin, D. D., van den Berge, M., Nickle, D. C., Bossé, Y., Tobin, M. D., Hall, I. P., Brightling, C. E., Wain, L. V. & Sayers, I., 1 Jan 2019, In : The Lancet Respiratory Medicine. 7, 1, p. 20-34 15 p.

    Research output: Contribution to journalArticle

  27. Published

    Cough in Patients With Lung Cancer: A Longitudinal Observational Study of Characterization and Clinical Associations

    Harle, A. S. M., Blackhall, F. H., Molassiotis, A., Yorke, J., Dockry, R., Holt, K. J., Yuill, D., Baker, K. & Smith, J. A., Jan 2019, In : Chest. 155, 1, p. 103-113 11 p.

    Research output: Contribution to journalArticle

  28. Published

    Fluorescent peptides for imaging of fungal cells

    Zhao, C., Mendive-Tapia, L. & Vendrell, M., Jan 2019, In : Archives of Biochemistry and Biophysics. 661, p. 187-195 9 p.

    Research output: Contribution to journalReview article

  29. Published

    Identification of B cell epitopes enhanced by protein unfolding and aggregation

    Eyes, T., Austerberry, J., Dearman, R., Johannissen, L., Kimber, I., Smith, N., Thistlethwaite, A. & Derrick, J., Jan 2019, In : Molecular immunology. 105, p. 181-189 8 p.

    Research output: Contribution to journalArticle

  30. Published

    “T2-high” in severe asthma related to blood eosinophil, exhaled nitric oxide and serum periostin

    U-BIOPRED Study Group, 2019, In : European Respiratory Journal. 53, 1, 1800938.

    Research output: Contribution to journalArticle

  31. Published

    2019 ARIA Care pathways for allergen immunotherapy

    The ARIA Working Group, 2019, In : Allergy: European Journal of Allergy and Clinical Immunology.

    Research output: Contribution to journalReview article

  32. Published

    A Randomized Trial of Dual-Acting Bronchodilator AZD8871 for Chronic Obstructive Pulmonary Disease

    Singh, D., Fuhr, R., Jimenez, L., Wählby Hamrén, U., Jauhiainen, A., Malice, M., Balaguer, V., Lei, A., Aggarwal, A., Astbury, C. & Psallidas, I., 2019, In : American Journal of Respiratory and Critical Care Medicine .

    Research output: Contribution to journalLetter

  33. Published

    A Trans-ancestral Meta-Analysis of Genome-Wide Association Studies Reveals Loci Associated with Childhood Obesity

    Bradfield, J. P., Vogelezang, S., Felix, J. F., Chesi, A., Helgeland, Ø., Horikoshi, M., Karhunen, V., Lowry, E., Cousminer, D. L., Ahluwalia, T. S., Thiering, E., Boh, E. T., Zafarmand, M. H., Vilor-tejedor, N., Wang, C. A., Joro, R., Chen, Z., Gauderman, W. J., Pitkänen, N., Parra, E. J. & 79 others, Fernandez-rhodes, L., Alyass, A., Monnereau, C., Curtin, J. A., Have, C. T., Mccormack, S. E., Hollensted, M., Frithioff-bøjsøe, C., Valladares-salgado, A., Peralta-romero, J., Teo, Y., Standl, M., Leinonen, J. T., Holm, J., Peters, T., Vioque, J., Vrijheid, M., Simpson, A., Custovic, A., Vaudel, M., Canouil, M., Lindi, V., Atalay, M., Kähönen, M., Raitakari, O. T., Van Schaik, B. D. C., Berkowitz, R. I., Cole, S. A., Voruganti, V. S., Wang, Y., Highland, H. M., Comuzzie, A. G., Butte, N. F., Justice, A. E., Gahagan, S., Blanco, E., Lehtimäki, T., Lakka, T. A., Hebebrand, J., Bonnefond, A., Grarup, N., Froguel, P., Lyytikäinen, L., Cruz, M., Kobes, S., Hanson, R. L., Zemel, B. S., Hinney, A., Teo, K. K., Meyre, D., North, K. E., Gilliland, F. D., Bisgaard, H., Bustamante, M., Bonnelykke, K., Pennell, C. E., Rivadeneira, F., Uitterlinden, A. G., Baier, L. J., Vrijkotte, T. G. M., Heinrich, J., Sørensen, T. I. A., Saw, S., Pedersen, O., Hansen, T., Eriksson, J., Widén, E., Mccarthy, M. I., Njølstad, P. R., Power, C., Hyppönen, E., Sebert, S., Brown, C. D., Järvelin, M., Timpson, N. J., Johansson, S., Hakonarson, H., Jaddoe, V. W. V. & Grant, S. F. A., 2019, In : Human Molecular Genetics.

    Research output: Contribution to journalArticle

  34. Published
  35. Published

    Acute kidney injury: an unusual complication of posaconazole use

    Otu, A., Bongomin, F., Kosmidis, C. & Denning, D. W., 2019, In : Journal of Chemotherapy. 30, 6-8, p. 380-383 4 p.

    Research output: Contribution to journalArticle

  36. Published

    Allergen challenge increases capsaicin evoked cough responses in allergic asthma

    Satia, I., Watson, R., Scime, T., Dockry, R. J., Sen, S., Ford, J. W., Mitchell, P. D., Fowler, S. J., Gauvreau, G. M., O'Byrne, P. M. & Smith, J. A., 2019, In : The Journal of allergy and clinical immunology.

    Research output: Contribution to journalArticle

  37. Published

    Allergenic and novel food proteins: State of the art and challenges in the allergenicity assessment

    Pali-Schoell, I., Verhoeckx, K., Mafra, I., Bavaro, S. L., Mills, E. N. C. & Monaci, L., 2019, In : Trends in Food Science and Technology. 84, p. 45-48

    Research output: Contribution to journalReview article

  38. Published

    Alopecia areata is characterized by dysregulation in systemic type 17 and type 2 cytokines, which may contribute to disease-associated psychological morbidity

    Bain, K. A., McDonald, E., Moffat, F., Tutino, M., Castelino, M., Barton, A., Cavanagh, J., Ijaz, U. Z., Siebert, S., McInnes, I. B., Astrand, A., Holmes, S. & Milling, S. W. F., 2019, In : British Journal of Dermatology.

    Research output: Contribution to journalArticle

  39. Published

    Antibiotic Treatment for Pneumonia Complicating Stroke: Recommendations From The Pneumonia in Stroke Consensus (PISCES) Group

    Kishore, A., Jeans, A., Garau, J., Bustamante, A., Kalra, L., Langhorne, P., Chamorro, A., Urra, X., Katan, M., Di Napoli, M., Westendorp, W., Nederkoorn, P. J., van de Beek, D., Roffe, C., Woodhead, M., Montaner, J., Meisel, A. & Smith, C., 2019, In : European Stroke Journal.

    Research output: Contribution to journalArticle

  40. Published

    Antigen presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria

    Melo Gonzalez, F., Kammoun, H., Evren, E., Dutton, E. E., Papadopoulou, M., Bradford, B. M., Tanes, C., Fardus-Reid, F., Swann, J., Bittinger, K., Mabbott, N. A., Vallance, B. A., Willinger, T., Withers, D. & Hepworth, M., 2019, In : Journal of Experimental Medicine.

    Research output: Contribution to journalArticle

  41. Published

    Arginine to lysine mutations increase the aggregation stability of a single chain variable fragment through unfolded state interactions

    Austerberry, J., Thistlethwaite, A., Fisher, K., Golovanov, A. P., Pluen, A., Esfandiary, R., van der Walle, C. F., Warwicker, J., Derrick, J. P. & Curtis, R., 2019, In : Biochemistry.

    Research output: Contribution to journalArticle

  42. Accepted/In press

    Aspergillosis

    Richardson, M. & Denning, D. W., 2019, (Accepted/In press) Control of Communicable Diseases: Laboratory practice. Wilke, B. & Heymann, D. (eds.). American Public Health Association, p. 40-47 7 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  43. Published

    Assessing arthritis in the context of cystic fibrosis

    Clarke, E. A., Watson, P., Freeston, J. E., Peckham, D. G., Jones, A. M. & Horsley, A., 2019, In : Pediatric Pulmonology.

    Research output: Contribution to journalArticle

  44. Published

    Assessment of and future perspectives on standards of CARE in invasive fungal disease

    Munoz, P., Ruiz Camps, I. & Richardson, M., 2019, In : The Journal of antimicrobial chemotherapy. 74, Supplement 2

    Research output: Contribution to journalArticle

  45. Published

    Association Between Serum Lipid Profile and Obstructive Respiratory Events During REM and Non-REM Sleep

    Bikov, A., Lazar, Z., Horvath, P., Tarnoki, D. L., Tarnoki, A. D., Fesus, L., Horvath, M., Meszaros, M., Losonczy, G. & Kunos, L., 2019, In : Lung.

    Research output: Contribution to journalArticle

  46. Published

    Attack, Flare-up or Exacerbation? The terminology preferences of patients with severe asthma

    Jones, K., Gibson, P., Yorke, J., Niven, R., Smith, A. & McDonald, V., 2019, In : Journal of Asthma.

    Research output: Contribution to journalArticle

  47. Published
  48. Published

    Auxarthron alboluteum related to non-dermatophytic toenail infection in Kurdistan region, Iraq: A case report

    Gharib, S. J., Abdullah, S. K. & Richardson, M. D., 2019, In : Medical Mycology Case Reports. 26, p. 53-56

    Research output: Contribution to journalArticle

  49. Published

    Bayesian Detection of Piecewise Linear Trends in Replicated Time-Series with Application to Growth Data Modelling

    Papastamoulis, P., Furukawa, T., van Rhijn, N., Bromley, M., Bignell, E. & Rattray, M., 2019, In : International Journal of Biostatistics.

    Research output: Contribution to journalArticle

  50. Published

    Benralizumab for the Prevention of COPD Exacerbations

    Criner, G. J., Celli, B. R., Brightling, C. E., Agusti, A., Papi, A., Singh, D., Sin, D. D., Vogelmeier, C. F., Sciurba, F. C., Bafadhel, M., Backer, V., Kato, M., Ramírez-venegas, A., Wei, Y., Bjermer, L., Shih, V. H., Jison, M., O’quinn, S., Makulova, N., Newbold, P. & 2 others, Goldman, M. & Martin, U. J., 2019, In : New England Journal Of Medicine.

    Research output: Contribution to journalArticle

  51. Published

    BET 2: Is sexual dysfunction a recognised sign of cauda equina syndrome in the ED?

    Angus, M. & Horner, D., 2019, In : Emergency medicine journal : EMJ. 36, 8, p. 508-510 3 p.

    Research output: Contribution to journalArticle

  52. Published

    Biologics for paediatric severe asthma: Trick or TREAT?

    Saglani, S., Bush, A., Carroll, W., Cunningham, S., Fleming, L., Gaillard, E. A., Gupta, A., Murray, C., Nagakumar, P., Paton, J., Roberts, G., Seddon, P. & Sinha, I., 2019, In : The Lancet Respiratory Medicine.

    Research output: Contribution to journalArticle

  53. Published

    Burden of fungal asthma in Africa: A systematic review and meta-analysis

    Kwizera, R., Musaazi, J., Meya, D. B., Worodria, W., Bwanga, F., Kajumbula, H., Fowler, S. J., Kirenga, B. J., Gore, R., Denning, D. W. & Barac, A., 2019, In : PLoS ONE. 14, 5, p. e0216568

    Research output: Contribution to journalArticle

  54. Published

    CD200R1 regulates eosinophilia during pulmonary fungal infection in mice

    Salek-Ardakani, S., Bell, T., Jagger, C., Snelgrove, R. J. & Hussell, T., 2019, In : European journal of immunology.

    Research output: Contribution to journalArticle

  55. Published

    Chemokine Receptor Redundancy and Specificity Are Context Dependent

    Dyer, D. P., Medina-Ruiz, L., Bartolini, R., Schuette, F., Hughes, C. E., Pallas, K., Vidler, F., Macleod, M. K. L., Kelly, C. J., Lee, K. M., Hansell, C. A. H. & Graham, G. J., 2019, In : Immunity. 50, 2, p. 378-389.e5

    Research output: Contribution to journalArticle

  56. Published

    Chronic pulmonary aspergillosis commonly complicates treated pulmonary tuberculosis with residual cavitation

    Page, I., Byanyima, R., Hosmane, S., Onyachi, N., Opira, C., Richardson, M., Sawyer, R., Sharman, A. & Denning, D., 2019, In : European Respiratory Journal.

    Research output: Contribution to journalArticle

  57. Published

    Comparison of CD8+ T cell accumulation in the brain during human and murine cerebral malaria

    Barrera, V., Haley, M., Strangward, P., Attree, E., Kamiza, S., Seydel, K., Taylor, T., Milner, D., Craig, A. & Couper, K., 2019, In : Frontiers in Immunology.

    Research output: Contribution to journalArticle

  58. Published

    Composition of airway bacterial community correlates with chest HRCT in adults with bronchiectasis

    O'neill, K., Einarsson, G. G., Rowan, S., Mcilreavey, L., Lee, A. J., Lawson, J., Lynch, T., Horsley, A., Bradley, J. M., Elborn, J. S. & Tunney, M. M., 2019, In : Respirology.

    Research output: Contribution to journalArticle

  59. Published

    Comprehensive coronary plaque assessment in patients with obstructive sleep apnea

    Bikov, A., Kolossváry, M., Jermendy, A. L., Drobni, Z. D., Tarnoki, A. D., Tarnoki, D. L., Forgó, B., Kovacs, D. T., Losonczy, G., Kunos, L., Voros, S., Merkely, B. & Maurovich-Horvat, P., 2019, In : Journal of Sleep Research.

    Research output: Contribution to journalArticle

  60. Published

    Contribution of airway eosinophils in airway wall remodeling in asthma: role of MMP-10 and MET

    U-BIOPRED Project Team, 2019, In : Allergy.

    Research output: Contribution to journalArticle

  61. Published

    Cough: New Pharmacology

    Smith, J. A. & Badri, H., 2019, In : Journal of Allergy and Clinical Immunology: In Practice. 7, 6, p. 1731-1738 8 p.

    Research output: Contribution to journalArticle

  62. Published

    Cough Rhythms in Asthma: Potential Implication for Management

    Sirat, L., Smith, J. A., Imran, S., Holt, K. J., Maidstone, R. J. & Durrington, H. J., 2019, In : The Journal of Allergy and Clinical Immunology: In Practice.

    Research output: Contribution to journalArticle

  63. Published
  64. Published

    Development and validation of the European QUALity (EQUAL) Score for Mucormycosis Management in Haematology

    Koehler, P., Mellinghoff, S., Lagrou, K., Alanio, A., Arenz, D., Hoenigl, M., Koehler, F. C., Lass-Flörl, C., Meis, J. F., Richardson, M. & Cornely, O. A., 2019, In : Journal of Antimicrobial Chemotherapy.

    Research output: Contribution to journalArticle

  65. Published

    Diagnosis and management of individuals with Fetal Valproate Spectrum Disorder; a consensus statement from the European Reference Network for Congenital Malformations and Intellectual Disability

    Clayton-Smith, J., Bromley, R., Dean, J., Journel, H., Odent, S., Wood, A., Williams, J., Cuthbert, V., Hackett, L., Aslam, N., Malm, H., James, G., Westbom, L., Day, R., Ladusans, E., Jackson, A., Bruce, I., Walker, R., Sidhu, S., Dyer, C. & 6 others, Ashworth, J., Hindley, D., Diaz, G. A., Rawson, M., Turnpenny, P. & Jackson, A., 2019, In : Orphanet Journal of Rare Diseases. 14, 1, p. 180

    Research output: Contribution to journalArticle

  66. Published

    Different definitions of atopic dermatitis: Impact on prevalence estimates and associated risk factors

    Nakamura, T., Haider, S., Colicino, S., Murray, C. S., Holloway, J., Simpson, A., Cullinan, P. & Custovic, A., 2019, In : British Journal of Dermatology.

    Research output: Contribution to journalArticle

  67. Published

    Differential associations of allergic disease genetic variants with developmental profiles of eczema, wheeze and rhinitis

    Clark, H., Granell, R., Curtin, J., Belgrave, D., Simpson, A., Murray, C., Henderson, A. J., Custovic, A. & Paternoster, L., 2019, In : Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

    Research output: Contribution to journalArticle

  68. Published

    Distal Consequences of Oral Inflammation

    Konkel, J., O'Boyle, C. & Krishnan, S., 2019, In : Frontiers in Immunology.

    Research output: Contribution to journalArticle

  69. Published

    Distinguishing Wheezing Phenotypes from Infancy to Adolescence: A Pooled Analysis of Five Birth Cohorts

    Oksel, C., Granell, R., Haider, S., Fontanella, S., Simpson, A., Turner, S., Devereux, G., Arshad, S. H., Murray, C. S., Roberts, G., Holloway, J. W., Cullinan, P., Henderson, J. & Custovic, A., 2019, In : Annals of the American Thoracic Society.

    Research output: Contribution to journalArticle

  70. Published

    Do Clinical Correlates of Knee Osteoarthritis Predict Outcome to Intra-Articular Steroid Injections?

    Maricar, N., Parkes, M., Callaghan, M., Felson, D. & O'Neill, T., 2019, In : Journal of Rheumatology.

    Research output: Contribution to journalArticle

  71. Published

    Dupilumab in Adolescents With Uncontrolled Moderate-To-Severe Atopic Dermatitis: Results From a Phase 2a and Subsequent Open-Label Extension Trial

    Cork, M. J., Thaci, D., Eichenfield, L., Arkwright, P., Hultsch, T., Davis, J. D., Zhang, Y., Zhang, Q., Chen, Z., Li, M., Ardeleanu, M., Teper, A., Akinlade, B., Gadkari, A., Eckert, L., Kamal, M., Ruddy, M., Graham, N. M. H., Pirozzi, G., Stahl, N. & 2 others, DiCioccio, A. T. & Bansal, A., 2019, In : British Journal of Dermatology.

    Research output: Contribution to journalArticle

  72. Published

    Dysregulation of the endothelial nitric oxide pathway is associated with airway inflammation in COPD

    Csoma, B., Bikov, A., Nagy, L., Tóth, B., Tábi, T., Szucs, G., Komlósi, Z. I., Müller, V., Losonczy, G. & Lázár, Z., 2019, In : Respiratory research. 20, 1

    Research output: Contribution to journalArticle

  73. Published

    Effects of baseline symptom burden on treatment response in COPD

    Martinez, F. J., Abrahams, R. A., Ferguson, G. T., Bjermer, L., Grönke, L., Voß, F. & Singh, D., 2019, In : International journal of chronic obstructive pulmonary disease. 14, p. 181-194 14 p.

    Research output: Contribution to journalArticle

  74. Published

    Effects of interleukin-6 receptor blockade on allergen-induced airway responses in mild asthmatics

    Revez, J. A., Bain, L. M., Watson, R. M., Towers, M., Collins, T., Killian, K. J., O'Byrne, P. M., Gauvreau, G. M., Upham, J. W. & Ferreira, M. A. R., 2019, In : Clinical and Translational Immunology. 8, 6, e1044.

    Research output: Contribution to journalArticle

  75. Published

    Efficacy and safety of bronchial thermoplasty in clinical practice: A prospective, longitudinal, cohort study using evidence from the UK Severe Asthma Registry

    Burn, J., Sims, A. J., Patrick, H., Heaney, L. G. & Niven, R. M., 2019, In : BMJ Open. 9, 6, e026742.

    Research output: Contribution to journalArticle

  76. Published

    Efficacy of aclidinium/formoterol 400/12 µg, analyzed by airflow obstruction severity, age, sex, and exacerbation history: pooled analysis of ACLIFORM and AUGMENT

    D'Urzo, A. D., Singh, D., Donohue, J. F., Kerwin, E. M., Ribera, A., Molins, E., Chuecos, F., Jarreta, D. & Gil, E. G., 2019, In : International journal of chronic obstructive pulmonary disease. 14, p. 479-491 13 p.

    Research output: Contribution to journalArticle

  77. Published

    Emerging targets for cough therapies; NK1 receptor antagonists

    Badri, H. & Smith, J. A., 2019, In : Pulmonary pharmacology & therapeutics. 59, p. 101853

    Research output: Contribution to journalArticle

  78. Published

    Endothelin-1 mediates Aspergillus fumigatus induced airway inflammation and remodelling.

    Labram, B., Namvar, S., Hussell, T. & Herrick, S., 2019, In : Clinical and Experimental Allergy.

    Research output: Contribution to journalArticle

  79. Published

    Enhanced fatty acid scavenging and glycerophospholipid metabolism accompanies melanocyte neoplasia progression in zebrafish

    Henderson, F., Johnston, H., Badrock, A., Jones, E., Forster, D., Nagaraju, R., Evangelou, C., Kamarashev, J., Green, M., Fairclough, M., Barinaga-Rementeria, I., He, S., Jagalska, E. S., Hollywood, K., Dunn, W., Spaink, H. P., Smith, M., Lorigan, P., Claude, E., Williams, K. & 2 others, Mcmahon, A. & Hurlstone, A., 2019, In : Cancer Research.

    Research output: Contribution to journalArticle

  80. Published

    Enhanced monocyte recruitment and delayed alternative macrophage polarisation accompanies impaired repair following myocardial infarction in C57BL/6 compared to BALB/c mice

    Toor, I. S., Rückerl, D., Mair, I., Thomson, A., Rossi, A. G., Newby, D. E., Allen, J. E. & Gray, G. A., 2019, In : Clinical and experimental immunology.

    Research output: Contribution to journalArticle

  81. Published

    Essential in vitro diagnostics for advanced HIV and serious fungal diseases: international experts’ consensus recommendations

    Bongomin, F., Govender, N. P., Chakrabarti, A., Robert-gangneux, F., Boulware, D. R., Zafar, A., Oladele, R. O., Richardson, M. D., Gangneux, J., Alastruey-izquierdo, A., Bazira, J., Boyles, T. H., Sarcarlal, J., Nacher, M., Obayashi, T., Worodria, W., Pasqualotto, A. C., Meya, D. B., Cheng, B., Sriruttan, C. & 6 others, Muzoora, C., Kambugu, A., Rodriguez Tudela, J. L., Jordan, A., Chiller, T. M. & Denning, D. W., 2019, In : European Journal of Clinical Microbiology and Infectious Diseases.

    Research output: Contribution to journalArticle

  82. Published

    Estimated burden of serious fungal infections in Ghana

    Ocansey, B. K., Pesewu, G. A., Codjoe, F. S., Osei-Djarbeng, S., Feglo, P. K. & Denning, D. W., 2019, In : Journal of Fungi. 5, 2, 38.

    Research output: Contribution to journalArticle

  83. Published

    Exhaled breath metabolomics reveals a pathogen-specific response in a rat pneumonia model for two human pathogenic bacteria: a proof-of-concept study

    van Oort, P. M. P., Brinkman, P., Slingers, G., Koppen, G., Maas, A., Roelofs, J. J. T. H., Schnabel, R., Bergmans, D. C., Raes, M., Goodacre, R., Fowler, S. J., Schultz, M. J., Bos, L. D. & BreathDx Consortium, 2019, In : American journal of physiology. Lung cellular and molecular physiology.

    Research output: Contribution to journalArticle

  84. Published

    Exhaled carbon monoxide levels in obstructive sleep apnoea

    Kis, A., Meszaros, M., Tarnoki, D. L., Tarnoki, A. D., Lazar, Z., Horvath, P., Kunos, L. & Bikov, A., 2019, In : Journal of Breath Research. 13, 3

    Research output: Contribution to journalArticle

  85. Published

    Exhaled Volatile Organic Compounds as Markers for Medication Use in Asthma

    U-BIOPRED Study Group, 2019, In : The European respiratory journal.

    Research output: Contribution to journalArticle

  86. Published

    Experimental steering of electron microscopy studies using prior X-ray Computed Tomography

    Starborg, T., O'Sullivan, J. D. B., Martins Carneiro, C., Behnsen, J., Else, K., Grencis, R. & Withers, P., 2019, In : Ultramicroscopy.

    Research output: Contribution to journalArticle

  87. Published

    Exploring the relevance and extent of small airways dysfunction in asthma: baseline data from the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) prospective cohort study

    ATLANTIS study group, Postma, D. S., Brightling, C., Baldi, S., Van den Berge, M., Fabbri, LM., Gagnatelli, A., Papi, A., Van der Molen, T., Rabe, KF., Siddiqui, S., Singh, D., Nicolini, G. & Kraft, M., 2019, In : The Lancet Respiratory Medicine.

    Research output: Contribution to journalArticle

  88. Published
  89. Published

    Extrafine triple therapy delays COPD clinically important deterioration vs ICS/LABA, LAMA, or LABA/LAMA

    Singh, D., Fabbri, L. M., Vezzoli, S., Petruzzelli, S. & Papi, A., 2019, In : International Journal of COPD. 14, p. 531-546 16 p.

    Research output: Contribution to journalArticle

  90. Published

    Fluticasone furoate/vilanterol versus fluticasone propionate in patients with asthma and exercise-induced bronchoconstriction

    Martin, N., Weiler, J. M., Pearlman, D., Jacques, L., Nunn, C., Forth, R., West, S., Dunn, K. & O'Byrne, P. M., 2019, In : The Journal of asthma : official journal of the Association for the Care of Asthma. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  91. Published

    Food Allergy in Adults: Substantial Variation in Prevalence and Causative Foods Across Europe

    Lyons, S. A., Burney, P. G. J., Ballmer-Weber, B. K., Fernandez-Rivas, M., Barreales, L., Clausen, M., Dubakiene, R., Fernandez-Perez, C., Fritsche, P., Jedrzejczak-Czechowicz, M., Kowalski, M. L., Kralimarkova, T., Kummeling, I., Mustakov, T. B., Lebens, A. F. M., van Os-Medendorp, H., Papadopoulos, N. G., Popov, T. A., Sakellariou, A., Welsing, P. M. J. & 5 others, Potts, J., Mills, E. N. C., van Ree, R., Knulst, A. C. & Le, T. M., 2019, In : Journal of Allergy and Clinical Immunology: In Practice.

    Research output: Contribution to journalArticle

  92. Published

    Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

    International COPD Genetics Consortium & Vestbo, J., 2019, In : Nature Genetics.

    Research output: Contribution to journalArticle

  93. Published

    Genome-wide effect of pulmonary airway epithelial cell–specific Bmal1 deletion

    Zhang, Z., Hunter, L., Wu, G., Maidstone, R., Mizoro, Y., Vonslow, R., Fife, M., Hopwood, T., Begley, N., Saer, B., Wang, P., Cunningham, P., Baxter, M., Durrington, H., Blaikley, J. F., Hussell, T., Rattray, M., Hogenesch, J. B., Gibbs, J., Ray, D. W. & 1 others, Loudon, A. S. I., 2019, In : The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. p. fj.201801682R

    Research output: Contribution to journalArticle

  94. Published

    Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium

    Cornely, O. A., Alastruey-izquierdo, A., Arenz, D., Chen, S. C. A., Dannaoui, E., Hochhegger, B., Hoenigl, M., Jensen, H. E., Lagrou, K., Lewis, R. E., Mellinghoff, S. C., Mer, M., Pana, Z. D., Seidel, D., Sheppard, D. C., Wahba, R., Akova, M., Alanio, A., Al-hatmi, A. M. S., Arikan-akdagli, S. & 54 others, Badali, H., Ben-ami, R., Bonifaz, A., Bretagne, S., Castagnola, E., Chayakulkeeree, M., Colombo, A. L., Corzo-león, D. E., Drgona, L., Groll, A. H., Guinea, J., Heussel, C., Ibrahim, A. S., Kanj, S. S., Klimko, N., Lackner, M., Lamoth, F., Lanternier, F., Lass-floerl, C., Lee, D., Lehrnbecher, T., Lmimouni, B. E., Mares, M., Maschmeyer, G., Meis, J. F., Meletiadis, J., Morrissey, C. O., Nucci, M., Oladele, R., Pagano, L., Pasqualotto, A., Patel, A., Racil, Z., Richardson, M., Roilides, E., Ruhnke, M., Seyedmousavi, S., Sidharthan, N., Singh, N., Sinko, J., Skiada, A., Slavin, M., Soman, R., Spellberg, B., Steinbach, W., Tan, B. H., Ullmann, A. J., Vehreschild, J. J., Vehreschild, M. J. G. T., Walsh, T. J., White, P. L., Wiederhold, N. P., Zaoutis, T. & Chakrabarti, A., 2019, In : The Lancet Infectious Diseases.

    Research output: Contribution to journalArticle

  95. Published
  96. Published

    Gut eosinophils and their impact on the mucus-resident microbiota

    Singh, G., Brass, A., Knight, C. & Cruickshank, S., 2019, In : Immunology.

    Research output: Contribution to journalArticle

  97. Published

    Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients

    Pillay, B., Avery, D. T., Smart, J. M., Cole, T., Choo, S., Chan, D., Gray, P., Mitchell, R., Wong, M., Campbell, D. E., Hsu, P., Ziegler, J. B., Peake, J., Alvaro, F., Picard, C., Bustamante, J., Neven, B., Cant, A. J., Uzel, G., Arkwright, P. & 7 others, Casanova, J-L., Su, H. C., Freeman, A., Shah, N., Hickstein, D. D., Tangye, S. G. & Ma, C. S., 2019, In : Journal of Clinical Investigation Insight.

    Research output: Contribution to journalArticle

  98. Published

    HLA-B and HLA-C differ in their nanoscale organization at cell surfaces

    Kennedy, P., Barthen, C., Williamson, D. & Davis, D. M., 2019, In : Frontiers in Immunology.

    Research output: Contribution to journalArticle

  99. Published

    Human TNF-Luc reporter mouse: A new model to quantify inflammatory responses

    Minshawi, F., White, M., Muller, W., Humphreys, N., Jackson, D., Campbell, B. J., Adamson, A. & Papoutsopoulou, S., 2019, In : Scientific Reports.

    Research output: Contribution to journalArticle

  100. Published

    Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients

    Geary, B., Walker, M. J., Snow, J. T., Lee, D., Pernemalm, M., Maleki-Dizaji, S., Azadbakht, N., Apostolidou, S., Barnes, J., Krysiak, P., Shah, R., Booton, R., Dive, C., Crosbie, P. A. & Whetton, A. D., 2019, In : Journal of Proteome Research. 18, 9, p. 3369-3382 14 p.

    Research output: Contribution to journalArticle

  101. Published

    IL-17-high asthma with features of a psoriasis immunophenotype

    U-BIOPRED Study Group, 2019, In : The Journal of allergy and clinical immunology.

    Research output: Contribution to journalArticle

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