Division of Infection, Immunity & Respiratory Medicine

Publications

  1. 2019
  2. Accepted/In press

    Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-1 provided imatinib resistance in chronic myeloid leukemia cells

    Kolba, M. D., Dudka, W., Zaręba-Kozioł, M., Kominek, A., Ronchi, P., Turos, L., Chroscicki, P., Wlodarczyk, J., Schwab, Y., Klejman, A., Cysewski, D., Srpan, K., Davis, D. M. & Piwocka, K., 8 Oct 2019, (Accepted/In press) In : Cell Death Dis.

    Research output: Contribution to journalArticle

  3. Accepted/In press

    Establishing genotype-phenotype correlation in USH2A-related disorders to personalise audiological surveillance and rehabilitation.

    Molina Ramirez, L., Lenassi, E., Ellingford, J., Sergouniotis, P., Ramsden, S., Bruce, I. & Black, G., 1 Oct 2019, (Accepted/In press) In : Otology and Neurotology.

    Research output: Contribution to journalArticle

  4. E-pub ahead of print

    Increased type 2 inflammation post rhinovirus infection in patients with moderate asthma

    Southworth, T., Pattwell, C., Khan, N., Mowbray, S. F., Strieter, R. M., Erpenbeck, V. J. & Singh, D., 23 Sep 2019, In : Cytokine. 125, p. 154857

    Research output: Contribution to journalArticle

  5. Accepted/In press

    Pseudomonas aeruginosa-derived volatile sulphur compounds promote distal Aspergillus fumigatus growth and a synergistic pathogen-pathogen interaction that increases pathogenicity in co-infection

    Scott, J., Sueiro Olivares, M., Ahmed, W., Heddergott, C., Zhao, C., Thomas, R., Bromley, M., Latgé, J. P., Krappmann, S., Fowler, S., Bignell, E. & Amich Elias, J., 23 Sep 2019, (Accepted/In press) In : Frontiers in Microbiology.

    Research output: Contribution to journalArticle

  6. E-pub ahead of print

    Identification of Functional and Druggable Sites in Aspergillus fumigatus Essential Phosphatases by Virtual Screening

    Thornton, B. P., Johns, A., Al-shidhani, R., Álvarez-carretero, S., Storer, I. S. R., Bromley, M. J. & Tabernero, L., 19 Sep 2019, In : International Journal of Molecular Sciences. 20, 18, p. 4636

    Research output: Contribution to journalArticle

  7. Published

    Rational Design, Structure–Activity Relationship, and Immunogenicity of Hypoallergenic Pru p 3 Variants

    Eichhorn, S., Hörschläger, A., Steiner, M., Laimer, J., Jensen, B. M., Versteeg, S. A., Pablos, I., Briza, P., Jongejan, L., Rigby, N., Asturias, J. A., Portolés, A., Fernandez-Rivas, M., Papadopoulos, N. G., Mari, A., Poulsen, L. K., Lackner, P., van Ree, R., Ferreira, F. & Gadermaier, G., 19 Sep 2019, In : Molecular Nutrition and Food Research. 1900336.

    Research output: Contribution to journalArticle

  8. Published

    Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

    Papoutsopoulou, S., Burkitt, M. D., Bergey, F., England, H., Rachel, H., Schmidt, L., Spiller, D., White, M., Paszek, P., Jackson, D., Martins Dos Santos, V. A. P., Selge, G., Prittchard, M. D., Campbell, B. J., Muller, W. & Probert, C. S., 11 Sep 2019, In : Frontiers in Immunology. 10, p. 2168

    Research output: Contribution to journalArticle

  9. Accepted/In press

    ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites

    Campbell, L., Hepworth, M., Whittingham-Dowd, J., Thompson, S., Bancroft, A., Hayes, K., Shaw, T., Dickey, B. F., Flammar, A-L., Artis, D., Schwartz, D. A., Evans, C. M., Roberts, I., Thornton, D. & Grencis, R., 5 Sep 2019, (Accepted/In press) In : Journal of Experimental Medicine.

    Research output: Contribution to journalArticle

  10. Accepted/In press

    Dupilumab in Adolescents With Uncontrolled Moderate-To-Severe Atopic Dermatitis: Results From a Phase 2a and Subsequent Open-Label Extension Trial

    Cork, M. J., Thaci, D., Eichenfield, L., Arkwright, P., Hultsch, T., Davis, J. D., Zhang, Y., Zhang, Q., Chen, Z., Li, M., Ardeleanu, M., Teper, A., Akinlade, B., Gadkari, A., Eckert, L., Kamal, M., Ruddy, M., Graham, N. M. H., Pirozzi, G., Stahl, N. & 2 others, DiCioccio, A. T. & Bansal, A., 3 Sep 2019, (Accepted/In press) In : British Journal of Dermatology.

    Research output: Contribution to journalArticle

  11. Published

    The burden of serious fungal infections in tajikistan

    Bobokhojaev, O. I., Osmanov, A., Aliev, S. P., Radjabzoda, A. S., Avgonov, Z. T., Manonov, S. T. & Denning, D. W., Sep 2019, In : Journal of Fungi. 5, 3, 68.

    Research output: Contribution to journalArticle

  12. Published

    The Human Lung Mycobiome in Chronic Respiratory Disease: Limitations of Methods and Our Current Understanding

    Weaver, D., Gago, S., Bromley, M. & Bowyer, P., Sep 2019, In : Current Fungal Infection Reports. 13, 3, p. 109-119 11 p.

    Research output: Contribution to journalReview article

  13. Accepted/In press

    Simultaneous SF6 and Nitrogen Multiple Breath Washout (MBW) to examine inherent differences in MBW outcomes

    Bayfield, K. J., Horsley, A., Alton, E., Irving, S., Bush, A. & Davies, J. C., 27 Aug 2019, (Accepted/In press) In : European Respiratory Journal Open Research.

    Research output: Contribution to journalArticle

  14. Published

    Fast and reliable PCR amplification from Aspergillus fumigatus spore suspension without traditional DNA extraction

    Fraczek, M., Zhao, C., Dineen, L., Lebedinec, R., Bowyer, P., Bromley, M. & Delneri, D., 20 Aug 2019, In : Current Protocols in Microbiology .

    Research output: Contribution to journalArticle

  15. Published

    Dust-mite inducing asthma: what advice can be given to patients?

    Custovic, A., Murray, C. S. & Simpson, A., 19 Aug 2019, In : Expert review of respiratory medicine. p. 1-8

    Research output: Contribution to journalArticle

  16. Accepted/In press

    Monthly variance in United Kingdom renal transplantation activity: a national retrospective cohort study

    Lowe, M., Maidstone, R., Poulton, K., Worthington, J., Durrington, H., Ray, D., van Dellen, D., Asderakis, A., Blaikley, J. & Augustine, T., 19 Aug 2019, (Accepted/In press) In : BMJ Open.

    Research output: Contribution to journalArticle

  17. Published

    Estimated Burden of Fungal Infections in Namibia

    Dunaiski, C. & Denning, D., 16 Aug 2019, In : Journal of Fungi. 5, 3, p. 75

    Research output: Contribution to journalArticle

  18. Accepted/In press

    Lung Clearance Index in Detection of Post-Transplant Bronchiolitis Obliterans Syndrome

    Driskel, M., Horsley, A., Fretwell, L., Clayton, N. & Al-Aloul, M., 16 Aug 2019, (Accepted/In press) In : European Respiratory Journal Open Research.

    Research output: Contribution to journalArticle

  19. Accepted/In press

    The future application of nanomedicine and biomimicry in reconstructive surgery

    Amin, K., Moscalu, R., Imere, A., Murphy, R., Barr, S., Tan, Y., Wong, R., Sorooshian, P., Zhang, F., Stone, J., Fildes, J., Reid, A. & Wong, J., 16 Aug 2019, (Accepted/In press) In : nanomedicine.

    Research output: Contribution to journalReview article

  20. E-pub ahead of print

    High throughput gene replacement in Aspergillus fumigatus

    Zhao, C., Fraczek, M., Dineen, L., Lebedinec, R., Macheleidt, J., Heinekamp, T., Delneri, D., Bowyer, P., Brakhage, A. A. & Bromley, M., 7 Aug 2019, In : Current Protocols in Microbiology .

    Research output: Contribution to journalArticle

  21. E-pub ahead of print

    Estimated burden of fungal infections in Sweden

    Özenci, V., Klingspor, L., Ullberg, M., Chryssanthou, E., Denning, D. W. & Kondori, N., 3 Aug 2019, In : MYCOSES.

    Research output: Contribution to journalArticle

  22. Published

    CT screening for lung cancer: Are we ready to implement in Europe?

    Balata, H., Evison, M., Sharman, A., Crosbie, P. & Booton, R., 1 Aug 2019, In : Lung Cancer. 134, p. 25-33 9 p.

    Research output: Contribution to journalReview article

  23. Published

    Transbronchial Lung Cryobiopsy in Idiopathic Pulmonary Fibrosis

    Lodhi, T., Hughes, G., Stanel, S., Chaudhuri, N. & Hayton, C., 30 Jul 2019, In : Advances in Therapy. p. 1-12 12 p.

    Research output: Contribution to journalArticle

  24. Accepted/In press

    A systematic evaluation of the diagnostic criteria for COPD and exacerbations used in randomized controlled trials on the management of COPD exacerbations

    Mathioudakis, A., Janner, J., Moberg, M., Alonso-Coello, P. & Vestbo, J., 29 Jul 2019, (Accepted/In press) In : European Respiratory Journal Open Research.

    Research output: Contribution to journalLetter

  25. Published

    Functional interactions between innate lymphoid cells and adaptive immunity

    Sonnenberg, G. F. & Hepworth, M., 26 Jul 2019, In : Nature reviews. Immunology.

    Research output: Contribution to journalArticle

  26. Published

    Kinetic modeling of DUSP regulation in Herceptin-resistant HER2-positive breast cancer

    Buiga, P., Elson, A., Tabernero, L. & Schwartz, J-M., 26 Jul 2019, In : Genes. 10, 568.

    Research output: Contribution to journalArticle

  27. Accepted/In press

    Gut eosinophils and their impact on the mucus-resident microbiota

    Singh, G., Brass, A., Knight, C. & Cruickshank, S., 18 Jul 2019, (Accepted/In press) In : Immunology.

    Research output: Contribution to journalArticle

  28. E-pub ahead of print

    Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

    International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 10351.

    Research output: Contribution to journalArticle

  29. Published

    Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs

    Fernandez-Soto, P., Bruce, A. J. E., Fielding, A. J., Cavet, J. S. & Tabernero, L., 16 Jul 2019, In : Scientific Reports. 9, 1, p. 10315

    Research output: Contribution to journalArticle

  30. Accepted/In press

    Recording obligatory cortical auditory evoked potentials in infants: quantitative information on feasibility and parent acceptability

    Munro, K., Purdy, S. C., Uus, K., Visram, A., Booth, R., Bruce, I., Marsden, A., Stone, M. & Van Dun, B., 16 Jul 2019, (Accepted/In press) In : Ear and hearing.

    Research output: Contribution to journalArticle

  31. Published
  32. Accepted/In press

    Microbial contamination of heater cooler units used in ECMO is not aerosolised into the environment: a single centre experience.

    Thomas, S., Moore, G., Stevenson, D., Otu, A. A., Vergidis, P., Barker, J., Ashworth, A., Exton, P. & Richardson, M., 12 Jul 2019, (Accepted/In press) In : Infection Control and Hospital Epidemiology.

    Research output: Contribution to journalArticle

  33. Accepted/In press

    Comparison of CD8+ T cell accumulation in the brain during human and murine cerebral malaria

    Barrera, V., Haley, M., Strangward, P., Attree, E., Kamiza, S., Seydel, K., Taylor, T., Milner, D., Craig, A. & Couper, K., 10 Jul 2019, (Accepted/In press) In : Frontiers in Immunology.

    Research output: Contribution to journalArticle

  34. Published

    Weighing the evidence for pharmacological treatment interventions in mild COPD; A narrative perspective

    Singh, D., D'Urzo, A. D., Donohue, J. F. & Kerwin, E. M., 8 Jul 2019, In : Respiratory research. 20, 1, 1108.

    Research output: Contribution to journalReview article

  35. Published

    Macrophages Assemble! But do they need IL-4R during Schistosomiasis?

    Rückerl, D. & Cook, P., 3 Jul 2019, In : European journal of immunology.

    Research output: Contribution to journalArticle

  36. E-pub ahead of print

    Old Dog New Tricks; Revisiting How Stroke Modulates the Systemic Immune Landscape

    Krishnan, S. & Lawrence, C. B., 2 Jul 2019, In : Frontiers in Neurology. 10

    Research output: Contribution to journalArticle

  37. Published

    Does understanding endotypes translate to better asthma management options for all?

    Custovic, A., Henderson, J. & Simpson, A., 1 Jul 2019, In : Journal of Allergy and Clinical Immunology. 144, 1, p. 25-33 9 p.

    Research output: Contribution to journalArticle

  38. Published

    Proteomic and Bioinformatic Analyses for the Identification of Proteins with Low Allergenic Potential for Hazard Assessment

    Krutz, N. L., Winget, J., Ryan, C. A., Wimalasena, R., Maurer-Stroh, S., Dearman, R. J., Kimber, I. & Gerberick, G. F., 1 Jul 2019, In : Toxicological Sciences. 170, 1, p. 210-222 13 p.

    Research output: Contribution to journalArticle

  39. Published

    ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”: AIRWAYS ICPs initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Santé) 
POLLAR (Impact of Air POLLution on Asthma and Rhinitis)
GARD Demonstration project

    AIRWAYS ICPs initiative, POLLAR (Impact of Air POLLution on Asthma and Rhinitis) & GARD Demonstration project, Jul 2019, In : Allergy: European Journal of Allergy and Clinical Immunology. 74, 7, p. 1219-1236 18 p.

    Research output: Contribution to journalReview article

  40. Published

    Asthma progression and mortality: the role of inhaled corticosteroids

    O'Byrne, P., Fabbri, L. M., Pavord, I. D., Papi, A., Petruzzelli, S. & Lange, P., Jul 2019, In : The European respiratory journal. 54, 1

    Research output: Contribution to journalReview article

  41. Published

    Stratification of asthma phenotypes by airway proteomic signatures

    U-BIOPRED Study Group, Jul 2019, In : The Journal of allergy and clinical immunology.

    Research output: Contribution to journalArticle

  42. Published

    Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

    U-BIOPRED Study Group, 27 Jun 2019, In : The European respiratory journal.

    Research output: Contribution to journalArticle

  43. Published

    Mycology Laboratory Diagnostic Capacity for Invasive Fungal Diseases in 2017: Results of a National Survey

    Schelenz, S., Owens, K., Guy, R., Rautemaa-Richardson, R., Manuel, R. J., Richardson, M., Moore, C. B., Enoch, D. A., Micallef, C., Howard, P., Agrawal, S. G., Johnson, E. M. & Muller-Pebody, B., 22 Jun 2019, In : Journal Of Infection.

    Research output: Contribution to journalArticle

  44. E-pub ahead of print

    Blood eosinophil counts in COPD patients compared to controls

    Kolsum, U., Southworth, T., Jackson, N. & Singh, D., 20 Jun 2019, In : The European respiratory journal.

    Research output: Contribution to journalArticle

  45. E-pub ahead of print

    Circadian rhythm of exhaled biomarkers in health and asthma

    Wilkinson, M., Maidstone, R., Loudon, A., Blaikley, J., White, I., Singh, D., Ray, D., Goodacre, R., Fowler, S. & Durrington, H., 20 Jun 2019, In : The European respiratory journal.

    Research output: Contribution to journalArticle

  46. Published

    The C-Type Lectin Receptor MGL senses Nacetylgalactosamine on the unique Staphylococcus aureus ST395 Wall Teichoic Acid

    Mnich, M. E., van Dalen, R., Gerlach, D., Hendriks, A., Xia, G., Peschel, A., van Strijp, J. A. G. & van Sorge, N. M., 20 Jun 2019, In : Cellular Microbiology.

    Research output: Contribution to journalArticle

  47. E-pub ahead of print

    Evaluation of LD Bio Aspergillus ICT lateral flow assay for IgG and IgM antibody detection in chronic pulmonary aspergillosis

    Hunter, E., Richardson, M. & Denning, D. W., 19 Jun 2019, In : Journal of clinical microbiology.

    Research output: Contribution to journalArticle

  48. Published

    A novel method for infant multiple breath washout: first report in clinical practice

    Shawcross, A., Murray, C., Pike, K. & Horsley, A., 18 Jun 2019, In : Pediatric Pulmonology.

    Research output: Contribution to journalArticle

  49. Published

    Genetic influences on the onset of obstructive sleep apnoea and daytime sleepiness: A twin study

    Szily, M., Tarnoki, A. D., Tarnoki, D. L., Kovacs, D. T., Forgo, B., Sung, J., Kunos, L., Meszaros, M., Muller, V. & Bikov, A., 17 Jun 2019, In : Respiratory research. 20, 1

    Research output: Contribution to journalArticle

  50. Published

    Pre-clinical Safety and Efficacy of Lentiviral Vector-Mediated Ex Vivo Stem Cell Gene Therapy for the Treatment of Mucopolysaccharidosis IIIA

    Ellison, S. M., Liao, A., Wood, S., Taylor, J., Youshani, A. S., Rowlston, S., Parker, H., Armant, M., Biffi, A., Chan, L., Farzaneh, F., Wynn, R., Jones, S. A., Heal, P., Gaspar, H. B. & Bigger, B. W., 14 Jun 2019, In : Molecular Therapy - Methods and Clinical Development. 13, p. 399-413 15 p.

    Research output: Contribution to journalArticle

  51. Published

    Strategies for the Induction of Immune Tolerance to Enzyme Replacement Therapy in Mucopolysaccharidosis Type I

    Ghosh, A., Liao, A., O'Leary, C., Mercer, J., Tylee, K., Goenka, A., Holley, R., Jones, S. A. & Bigger, B. W., 14 Jun 2019, In : Molecular Therapy - Methods and Clinical Development. 13, p. 321-333 13 p.

    Research output: Contribution to journalArticle

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