Prof Carlo Berzuini PhD

Professor in Biostatistics

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Overview

 

  • 2014: co-winner of a HORIZON 2020 European Commission Grant for the development of new early cancer diagnostics
  • since 2012:   Visiting Professor, Statistical Laboratory, Centre for Mathematical  Sciences, University of Cambridge,  UK
  • since 2012:   Visiting Professor, Department of Brain and Behavioural Sciences, University of Pavia, Italy
  • 2013-:            Master Course in Medical and Genomic Statistics, University of Pavia, Italy; teacher and Faculty member
  • since 2012:  University of Manchester, Professor of Biostatistics
  • since 2012:   Principal Investigator of  european research collaboration in Methods of Causal Inference for genomic epidemiology, within the MIMOmics Project, supported by the European Community under the FP7-HEALTH-2012-INNOVATION scheme
  • since 2013 :   Statistical Reviewer for Translational Research applications to Cancer Research UK
  • since 2013 :   involved in the creation and organization of a MSc in Biostatistics of the Faculty of Medical and Human Sciences of the University of Manchester.
  • (2007 - 2013)      Royal Statistical Society Study Group in Bioinformatics, proponent and chair
  • (2010-2012)   Master Course in Genetic and Molecular Epidemiology, University of Pavia, Pavia, Italy; teacher and Faculty member
  • (2001-2008) Visiting Professor, and Research Associate with Core Honorarium and Project Leader capacity, at the Biostatistics Unit of the Medical Research Council, Cambridge, United Kingdom (2006 MRC Biostatistics Unit QQR Review Committee Report

 

Biography

Carlo Berzuini got his secondary studies Diploma from the Liceo Scientifico "Giovio", Como, Italy, with top grades (60/60). He was then awarded a bourse by the Collegio Ghislieri of Pavia, which fully supported his undergraduate and MSc studies, completed in 1974 with a «cum laude» degree in bioengineering.

He now holds a Research Chair in Biostatistics at the University of Manchester (2011-), United Kingdom. After his employment as Professor of Biostatistics at the italian University of Pavia (1983-2008), he joined the Faculty of Mathematics of the University of Cambridge (2009-2011), where he, encouraged by Prof. Dawid, won an Isaac Newton Institute Award for research in Causal Inference. In Cambridge he also worked at the Cambridge Biostatistics Unit of the Medical Research Council, where he obtained (as Project PI) EU funds as part of the EU-funded pre-2007 Bloodomics Consortium, and used them to establish a MRC-BSU team of statistical geneticists. At Cambridge University he also acted as scientific advisor at the Department of Gastroenterology and, as a member of the Cambridge Inflammatory Bowel Disease (IBD) Research Group, he joined a large UK consortium for the study of genetic determinants of IBD. In 2011 he got the Manchester Chair.

As a leading expert in Statistical Genomics (190990) and Causal Inference (190970), and author of landmark contributions in Causative Interaction, Mediation and Mendelian Randomization, in 2009 he has organized in Cambridge the first major international conference on Causal Inference, jointly with L.Bernardinelli and A.P. Dawid. He has then lead-edited a landmark and successful book on Statistical Causality, for Wiley.

In 2007-2013 he was proponent and chair of the Royal Statistical Society Study Group in Bioinformatics, and Member of the Royal Statistical Society Council.

In 2014, his collaboration with Cambridge Abcodia Ltd for developing a biomarker-based approach to early diagnosis of pancreatic cancer earned him a Horizon 2020 nomination. He has participated with PI capacity in several European Research Projects. For decades he has been doing undergraduate, master and post-doc level teaching in top academic venues (Cambridge, Manchester, Pavia, Leiden, Aarhus, etc.). He authored publicly available R and Stan software. He has been statistical reviewer for such research funding bodies as MRC and NIHR and prestigious statistical and medical journals (https://publons.com/researcher/1669670/carlo-berzuini/).

A partial record of his peer reviewing activity for scientific journals can be found in Publons. In addition, he has been statistical reviewer for such research funding bodies as MRC and NIHR. See also https://orcid.org/0000-0001-6056-04

Qualifications

2014: invited talk on "Biomarker based early ptediction of pre-clinical cancer", InterOmics Annual Meeting, September 23-26, 2014, Rome.

2014: invited talk on "Causal Mediation and Mechanistic Interaction Analysis, with applications in Genomic Medicine", UNAM/ITAM Universities, Mexico DF, Mexico, 30th of July, 2014.

2014: invited talk on "Causal Inference methods to probe the molecular mechanisms of disease", International Conference on "Bringing Maths to Life", 27-29 october 2014 , Centro Congressi Federico II, Napoli, Italy

2014: one-week Course on "Causality in Health Sciences",  Department of Brain and  Behavioural Sciences, University of Pavia, Italy,  26-30 may 2014 

2014: invited talk on "Mechanistic interaction and other causal inference tools, with an application in the investigation of molecular mechanisms in Multiple Sclerosis". one-dayorkshop on "The Statistical Contributions of A. Philip Dawid: Causal Inference, Graphical Models and Prediction", Wednesday 30th
April 2014, Centre for Mathematical Sciences of the University of Cambridge

2014: invited lecturer on the topic of “Causality in Genomics” at the International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics (CIBB2014), Cambridge 26-28 June 2014.  

2013: invited discussant at the International Workshop on "Recent Advances in Statistical Inference: Theory and Case Studies", University of Padova, Italy, march 21–23, 2013.

2012; Vote Seconder and Discussant at the Read Paper on by Imai et al., Royal Statistical Society, London

2012: Isaac Newton Institute of Mathematics, Cambridge: ... (video)

2011 Invited Lecture on "Mechanistic Interaction", International Workshop "Causal Inference in the Health Sciences", University of Bologna, May 27-28.

2010 Invited talk : ”Causal Inference in Genetic Epidemiology”, Leiden University Medical Center. Department of Medical Statistics and Bioinformatics. 21 september.

2010 Invited Discussant. Ninth Valencia International Meeting on Bayesian Statistics, Benidorm (Alicante, Spain). June 2010. Discussant of the paper ”Incorporating Biological Information in Bayesian Models for the Selection of Pathways and Genes”, by Vannucci and Stingo.

2010 Invited Lecture at the Workshop on ”Epidemiology, Risk and Genomics”, organized by the Department of History and Biomedical Science in Society, University of Cambridge. January 2010.

2009 Invited lecture on "The investigation of genetic patterns of coronary artery disease within a predictive and a causal perspective", Statistical Laboratory, Centre for Mathematical Sciences, University of Cambridge. Monday 11 May 2009, 16:30-17:30

March 2009 Invited talk : ”Identifiability of Sequential Action Plans”. International Meeting on ”Causal Inference : the State of the Art”, Cambridge.

2008 Invited talk : ”Development and Prequential Validation of a genome wide predictor of disease occurrence : a Sequential Monte Carlo approach”. XXIVth International Biometric Conference, July 13-18t, 2008, Dublin.

 

RECENT AWARDS:

2012: recipient of an award from the Isaac Newton Trust for research in statistical methods for causal inference at the Centre for Mathematical Science of Cambridge University

2009-2012: awarded MRC Research Grant G0802320, for methodological research on "Genetic Variation, Disease Prediction and Causation"

Memberships of committees and professional bodies

  • (2014) Program Committee member and Reviewer. Uncertainty in Artificial Intelligence 2014 (UAI2014) Conference, Quebec, Ontario
  • (2014) Senior Program Committee member and reviewer, AISTATS 2014, Reykjavik
  • (2013) Program Committee member and reviewer, Conference  on Uncertainty in Artificial  Intelligence 2013, Washington
  • (2007-2013)  Committee member, Medical Section of the Royal Statistical Society

Areas of expertise

  • Q Science (General) - Biostatistics, Epidemiology, mathematics/ statistics, Mathematical modelling, genomics, causality

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