Chloroplasts convert light into chemical energy fuelling life on earth. They contain their own expression apparatus and set of genes. Transplastomic technologies allow precise targeted integration of trait genes into chloroplasts without marker genes. Industrial and therapeutic proteins expressed in chloroplasts accumulate to extraordinarily high levels providing an attractive production platform for manufacture of high-value products for industry and health, which is both sustainable and carbon-neutral. Maternal inheritance of chloroplast genes prevents the pollen-mediated spread of transgenes providing a natural form of gene containment for the next generation of Biotech crops. Biotechnological applications of this new and exciting area of science are underpinned by fundamental research on the genes present in chloroplasts.
The University of Manchester, UK
Genetics Laboratory, Dept of Biochemistry, University of Oxford, UK
EMBO Long Term Fellow. Dept. de Biologie Moleculaire, Geneva, Switzerland
PhD JIC, Norwich Research Triangle, UK
MA Biochemistry (with Chemical Pharmacology), University of Oxford, UK