Having completed my BSc in Biomedical Sciences at the University of Manchester, including one year industrial experience in Investigative and Translational Pathology at AstraZeneca UK, I am currently undertaking a PhD in Immunology under the supervision of Professor Andrew MacDonald and Dr John Grainger.
My specific research interests lie in the field of cancer immunotherapy, and my doctoral research aims to elucidate the mechanism by which a novel mycobacterial co-therapy, IMM-101, enhances tumour cell killing and prolongs surivival in patients with advanced pancreatic (and other) cancers. Specifically, this rearch aims to discover the following:
- What immune cell types are preferentially activated by IMM-101 both local and distal to the injection site?
- By what mechanism is the local immune reaction translated to a systemic immune response?
- Does IMM-101 enhance tumour immune cell infiltration?