Dr Alexander HorsleyMA MBChB MRCP PhD

Senior Lecturer (Hon Cons)

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Dr Horsley is an NIHR-funded clinical academic at the University of Manchester and consultant at the Manchester Adult Cystic Fibrosis Centre. He is academic lead for the CF Centre where he leads a programme of basic science and clinical research as part of The University of Manchester NIHR Biomedical Research Centre in Respiratory Medicine. His main work focusses on novel technologies and clinical applications for lung clearance index (LCI), how this relates to clinical outcomes and imaging, and encompasses all age groups from infants to adults. He is deputy director of the NIHR Manchester Clinical Research Facility at Wythenshawe Hospital, and leads a wide range of clinical trials in CF, including phase 1, both as principal and chief investigator. Dr Horsley has contributed to national policy on CF medications, to international guidelines on multiple breath washout, and is chief editor and author of the Oxford University Press Handbook on CF.


1991-1994  - Cambridge University, MA(Cantab) (1st)

1994-1997 - Edinburgh University. MBChB (Honours, Gold Medal)

2003            MRCP (Ed)

2003-2005 - Respiratory SpR training, Yorkshire Deanery

2005-2008 - PhD (Edinburgh University) "Non-invasive assessment of ventilation maldistribution in lung disease using multiple breath inert gas washouts"

2008-2010 - Respiratory SpR training, SW Scotland Deanery

2010-2011 - CF Trust Senior Training Fellow, Manchester Adult CF Centre

2011-2012 - Pickering fellow, Manchester University / Manchester Adult CF Centre

2013-2018 - NIHR Clinician Scientist Fellowship, University of Manchester

2013 -         Senior Lecturer, University of Manchester. Honorary Consultant, Wythenshawe Hospital



MA (Cantab) 1997 (1st class)

MBChB (Edinburgh) 1997 (Honours, and Ettles Gold Medal for most distinguished graduate)

MRCP (Edinburgh) 2002

PhD (Edinburgh) 2009

CCST Respiratory and General Internal Medicine, 2009

Memberships of committees and professional bodies

European Respiratory Society

European Cystic Fibrosis Society

British Thoracic Society

Royal College of Physicians (Edinburgh)

Biology, Medicine and Health (BMH) Domains


  • Cystic Fibrosis, Lung physiology, Lung Clearance Index, Lung infection, Lung imaging, Clinical Trials

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