Prof Brian Bigger PhD
Professor of Cell and Gene Therapy

Overview
- Professor of Cell And Gene Therapy, University of Manchester
- Head of Business Engagement, School of Biological Sciences
- Chairman, European Study Group on Lysosomal Diseases
Biography
Dr Bigger was awarded a Bachelors degree from the University of Bath in Applied Biology. His PhD was conducted in the Gene Therapy Research Group, Imperial College, London, where he worked with Professor Charles Coutelle on developing a gene delivery vehicle for mitochondrial gene therapy. On completion of his PhD in 2000, Dr Bigger joined Dr Mike Themis, Imperial College, London to work on a Wellcome Trust collaborative project with Cancer Research UK, investigating gene delivery to stem cells for liver diseases. In 2004 he joined Dr Suzanne Watt’s group in Oxford University and the National Blood Service as a Senior Research Scientist to work on mechanisms of stem cell homing. In 2006 Dr Bigger set up the Stem Cell & Neurotherapies laboratory at the University of Manchester and the Royal Manchester Children's hospital.
Memberships of committees and professional bodies
American Society of Gene & Cell Therapy
The European Society of Gene & Cell Therapy
The British Society for Gene & Cell Therapy
The European Study Group on Lysosomal Diseases
The Brains for Brain European Network
Research Networks and Beacons
Biology, Medicine and Health (BMH) Domains
Keywords
- gene therapy, lysosomal diseases, stem cells, Regenerative Medicine, haematopoietic stem cells, neuropathology, glioma, glioblastoma, stem cell gene therapy, mucopolysaccharidosis, sanfilippo
Related information
Publications
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review